RNA Tag METTL3 Drives Lung Scarring by Destabilizing a Key Fat-Droplet Protein
New research shows that the RNA methyltransferase METTL3 promotes lipid deposition and pulmonary fibrosis by destabilizing the messenger RNA of ...
Tag: METTL3
Chemical Tags on RNA Drive Cancer Spread and Treatment Failure, Review Finds
A comprehensive review in Molecular Cancer details how chemical modifications to RNA molecules regulate tumor metastasis and therapy resistance, opening ...
Chemical Tags on RNA Take Center Stage in Cancer’s Growth and Immune Evasion
A new review in Molecular Cancer details how the abundant RNA mark m6A drives cancer growth, immune evasion and treatment ...
RNA Tagging Machine Behind Endometriosis Blood Vessel Growth Revealed
Scientists have identified how the m6A reader protein YTHDF3 boosts PFKFB3 translation to fuel the pathological angiogenesis that sustains endometriosis ...
Hypoxia Rewires RNA Methylation to Drive Pancreatic Neuroendocrine Tumor Growth
A new study reveals how low oxygen strips m6A methylation marks from tumor cell RNA, unleashing a signaling cascade that ...
RNA Methylation Enzyme METTL3 Shields the Aging Ear from Inflammatory Damage
New research shows that the RNA methyltransferase METTL3 protects against age-related hearing loss by stabilizing NFKBIA mRNA through m6A modification ...
Lactate Signals and RNA Tags May Shape Post-Hemorrhage Depression, Review Proposes
A new review proposes that histone lactylation and m6A RNA methylation may link acute brain hemorrhage to long-term depression, anxiety, ...
Hidden RNA Switch Helps Esophageal Cancer Evade Ferroptotic Cell Death
A new study reveals that the m6A-stabilized long non-coding RNA SSTR5-AS1 helps esophageal cancer cells resist ferroptosis by recruiting FAM120A ...
METTL3 Emerges as a Molecular Hub Driving Tumor Immune Escape
A new review in the Journal of Translational Medicine details how the RNA methyltransferase METTL3 drives tumor immune escape through ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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