Lab Evolution’s Short Reach: E. coli Experiments Sample Less Than Half of Possible Amino Acid Swaps
A new analysis of roughly 25,000 amino acid substitutions from evolved E. coli shows that adaptive laboratory evolution samples less ...
Tag: metabolic engineering
Engineered Bacterium Turns Ethanol Into Cinnamic Acid in First-of-its-Kind Feat
Researchers at RIKEN have engineered the methylotrophic bacterium Methylorubrum extorquens PA1 to produce cinnamic acid directly from ethanol by repairing ...
Poisons Into Profits: Microbes Turn Biomass Toxins Into Fuel Boosters
A new review argues that toxic by-products of biomass pretreatment, from furfural to acetate, can be engineered into microbial feedstocks ...
Engineered bacteria set record yields for cancer drug romidepsin
Researchers engineered a Burkholderia chassis with resin-assisted fermentation and promoter tuning to raise romidepsin yields to a record 1,109.4 milligrams ...
Single Genetic Switch Drives Gene Expression in Both Bacteria and Yeast
KAIST researchers have engineered a hybrid promoter that preserves its relative strength ranking across E. coli and yeast, enabling the ...
Engineered Bacteria Churn Out Record Yields of Sustainable Isobutylamine
Researchers engineered Corynebacterium glutamicum to produce isobutylamine from sugars and waste feedstocks at a record 33.2 grams per liter, revealing ...
Engineered Bacterial Promoters Supercharge Gene Expression in Lactococcus cremoris
Researchers have identified and engineered a set of exceptionally strong constitutive promoters from Lactococcus cremoris, expanding the genetic toolbox for ...
Fungal Genome Hotspots Supercharge Production of Plant-Derived Drug Physcion
Scientists harnessed piggyBac transposon mapping and Hi-C chromatin analysis in Penicillium rubens to identify expression hotspots that boosted production of ...
Shotgun genetic engineering screens millions of metabolic pathways in mammalian cells
Researchers have developed shotgun genetic engineering, a method that screens millions of randomly assembled metabolic pathways in mammalian cells and ...
Engineered E. coli strains keep fragile nitro compounds alive for green chemistry
Researchers have engineered E. coli strains carrying up to 15 nitroreductase gene deletions that retain and biosynthesize diverse nitroaromatic compounds, ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!