Engineered Bacteria Churn Out Record Yields of Sustainable Isobutylamine
Researchers engineered Corynebacterium glutamicum to produce isobutylamine from sugars and waste feedstocks at a record 33.2 grams per liter, revealing ...
Tag: metabolic engineering
Engineered Bacterial Promoters Supercharge Gene Expression in Lactococcus cremoris
Researchers have identified and engineered a set of exceptionally strong constitutive promoters from Lactococcus cremoris, expanding the genetic toolbox for ...
Fungal Genome Hotspots Supercharge Production of Plant-Derived Drug Physcion
Scientists harnessed piggyBac transposon mapping and Hi-C chromatin analysis in Penicillium rubens to identify expression hotspots that boosted production of ...
Shotgun genetic engineering screens millions of metabolic pathways in mammalian cells
Researchers have developed shotgun genetic engineering, a method that screens millions of randomly assembled metabolic pathways in mammalian cells and ...
Engineered E. coli strains keep fragile nitro compounds alive for green chemistry
Researchers have engineered E. coli strains carrying up to 15 nitroreductase gene deletions that retain and biosynthesize diverse nitroaromatic compounds, ...
Metabolism Holds the Key to Stronger CAR T Cell Therapies, Review Argues
A Nature Reviews Cancer review argues that metabolism, from CAR design and manufacturing conditions to the patient's diet, is a ...
Shotgun genetic engineering lets mammalian cells stumble onto new metabolic pathways
A Nature Biotechnology commentary highlights how shotgun genetic engineering, which tests vast random combinations of genes in mammalian cells, enabled ...
Shotgun genetic engineering lets mammalian cells test millions of designs at once
Researchers have developed shotgun genetic engineering, a multiplexed strategy that screens millions of combinatorial genetic designs in mammalian cells within ...
CRISPR Knockout of a Single Gene Supercharges Soybean’s Health-Boosting Isoflavones
Researchers used CRISPR/Cas9 to knock out the GmMYB100 repressor gene in soybean, boosting seed daidzein levels nearly threefold and genistein ...
Master Switch Found: Single Gene Controls the Purple Pigments of Black Goji Berry
Researchers have identified the R2R3-MYB transcription factor LrMYB113 as a key regulator that directly activates anthocyanin biosynthesis genes in black ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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