Researchers have revealed that the glycolytic enzyme PFKFB4 accelerates hepatocellular carcinoma growth by stimulating lactate-driven histone lactylation to polarize tumor-associated ...
An integrated transcriptomic atlas of the human maternal-fetal interface reveals a conserved inflammatory macrophage program governed by WTAP that is ...
Researchers using single-cell and spatial genomics have mapped cardiac inflammaging in mice, discovering that age-related inflammation and fibrosis concentrate primarily ...
A new study reveals that the lipid mediator Resolvin D5 reprograms macrophage metabolism via GPR32 signaling, impairing the immune system's ...
A study reveals that type I interferon-induced viperin enables Mycobacterium tuberculosis survival in macrophages by suppressing the protective COX-2, PGE2, ...
A new study shows that the leukaemia gene TET2 directly controls the RNA-regulating protein AGO2, and reducing AGO2 impaired leukaemia ...
In a mouse model of endometriosis, macrophage-derived migrasomes reached ectopic lesions and promoted fibrotic remodeling alongside TGF-β/Smad pathway activation.
A hydroethanolic extract of Erycibe paniculata showed antimalarial, anticancer and anti-inflammatory effects in cell-based laboratory tests with no cytotoxicity observed.
A new study reveals that SPP1-positive tumor-associated macrophages promote cervical cancer progression by activating the NF-κB pathway in tumor cells ...
A study in cell culture and ApoE-deficient mice demonstrated that extracellular sulfatase SULF2 released by senescent endothelial cells promotes early-stage ...
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