When Bone Marrow Macrophages Deceive: Six Cases That Blur the Line Between Reactive and Cancerous
A new case series documents six bone marrow specimens in which benign, reactive histiocyte proliferations closely mimicked cancer, underscoring the ...
Tag: macrophages
Single-Cell Study Reveals Three Distinct Fates of Macrophages Infected by Gammaherpesvirus
A single-cell RNA sequencing study of murine gammaherpesvirus 68 reveals that macrophage infection can follow three distinct outcomes, a restricted ...
Macrophages Turned Into Living Transducers Could Decode Cancer’s Hidden Signals
Japanese researchers have built a microfluidic chip that uses human macrophages as living biological transducers, converting unknown cancer-cell-derived signals into ...
Immune Cells in Knee Joints Show Lipid-Driven Inflammation, Study Finds
A new single-cell study identifies the enzyme LTA4H in inflammatory myeloid cells as a link between lipid metabolism and knee ...
Immune Evasion in Metastatic Colorectal Cancer May Start Outside the Tumor Cell, Study Finds
An international research team reports that the sphingosine-1-phosphate signaling long thought to operate inside colorectal cancer cells instead builds an ...
Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts ...
Rival immune messengers turn out to be secret partners in healing
A Nature Communications study shows that the proinflammatory cytokine TNF acts mainly as a costimulator of IL-4-driven gene expression in ...
Cellular Nibbling: How Trogocytosis Shapes Immunity, Cancer, and Infection
A new review examines how trogocytosis, the process by which cells nibble membrane fragments from one another, shapes immune regulation, ...
Cell Maps of Endometriosis Reveal Nerve and Immune Hubs That May Drive Pain
A high-resolution spatial transcriptomic atlas of human ovarian and peritoneal endometriosis lesions reveals conserved fibroblast niches and sensory neuroimmune interactions ...
After Sepsis, Macrophages Fall Silent: Mouse Study Maps the Immune Collapse Behind Deadly Secondary Pneumonia
A two-hit mouse model reveals that sepsis leaves macrophages functionally silenced, blunting lung cytokine and chemokine responses to secondary Pseudomonas ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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