Review links macrophage mitochondrial imbalance to atherosclerosis progression
A 2026 review finds that experimental manipulation of macrophage mitochondrial quality control can change plaque development, but most supporting evidence ...
Tag: macrophages
RNase 2 shapes macrophage antiviral responses through targeted tRNA cleavage
A study in human macrophages found that RNase 2 supports antiviral gene expression and selectively generates transfer-RNA fragments during responses ...
Tuberculosis bacterium resists innate immune clearance in mouse models
Mouse infection experiments show that Mycobacterium tuberculosis remains difficult for innate immunity to clear across ultra-low-dose, microbiota-primed, and Legionella-primed models.
S. anginosus supernatant activates macrophages in gastric cancer models
Laboratory experiments linked Streptococcus anginosus culture supernatant to NLRP3-related macrophage activation and tumor-associated cellular changes, while an observational tissue analysis ...
TIMD4-targeted nanoparticles reduce colitis inflammation in mice
A macrophage-targeted TIMD4 peptide nanoparticle reduced inflammation and monocyte recruitment in a mouse colitis model without establishing clinical benefit in ...
Small spatial-transcriptomics study links metabolism to T-cell exclusion in esophageal adenocarcinoma
A small clinical study linked lipid metabolism and mitochondrial respiration to low CD8-positive T-cell infiltration in esophageal adenocarcinoma using spatial ...
Women’s blood transcriptomics link hypothyroidism and subclinical atherosclerosis
An exploratory whole-blood analysis identified a shared B-cell-associated gene signature in women with hypothyroidism and subclinical atherosclerosis, but small samples ...
Systematic review finds limited direct evidence of macrophage environmental memory
A systematic review of 119 studies found that only four directly demonstrated persistence or altered recall in macrophages or monocytes ...
Chimeric RNAs produce immune proteins that tune inflammation
A mouse immune-cell study links inflammation-induced chimeric RNA formation to a functional fusion protein that sharpens the trade-off between bacterial ...
Review maps bidirectional mitochondrial transfer across the osteoimmune microenvironment
A 2026 review finds that mitochondrial transfer between skeletal and immune cells can support bone homeostasis or promote disease, depending ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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