Hidden bone marrow progenitor offers alternative route to macrophage production
Researchers have identified a rare CD4-lineage progenitor in adult mouse bone marrow that generates macrophages, neutrophils and erythroid cells independently ...
Tag: macrophages
Review Maps Metabolic Targets Across Pulmonary Fibrosis Cell Types
A 2026 review maps altered glucose, lipid and amino-acid metabolism across four major lung cell populations and identifies promising but ...
Synthetic Peptide IL15.3 Calms Inflamed Immune Cells on Multiple Fronts
The synthetic antimicrobial peptide IL15.3 reduced inflammatory signaling in LPS-stimulated macrophages through coordinated transcriptional and proteomic changes, with low cytotoxicity ...
New Chalcone Compound B15 Eases Acute Lung Injury in Mice by Blocking p38 MAPK Signaling
Researchers designed a phenylthioether chalcone compound, B15, that directly binds p38 MAPK and reduced inflammation, oxidative stress and lung tissue ...
Titanium Implant Surfaces Reassessed Through Bone Remodelling and Osteoimmunology
A new review argues that titanium implant surfaces engineered by electrical discharge machining and diamond-like carbon coatings must be evaluated ...
How Antiviral Innate Immunity Shapes Viral Myocarditis Outcomes
A new review maps how RNA- and DNA-sensing innate immune pathways determine whether cardiotropic viral infection resolves or progresses to ...
Engineered IL-10-Secreting Macrophages Ease Colitis Symptoms in Mice
A preclinical mouse study found that intraperitoneally delivered macrophages engineered to secrete IL-10 reduced disease activity, preserved colon length, and ...
Spatial gene map reveals compartment-specific reprogramming in inflamed fatty livers
A spatial transcriptomics study of 16 MASH patients and eight controls maps compartment-specific CYP450 suppression, immune activation, and disrupted cell-cell ...
AI Maps Glioma Ecosystems and Exposes a Macrophage-Driven Vulnerability in Glioblastoma
An AI-driven single-cell and spatial multi-omics study defines three glioma ecosystem states and shows that a hypoxic myeloid-mesenchymal state independently ...
Bacterial Effector Kinase Drives Heat Shock Response in Legionella-Infected Macrophages
Multi-deletion mutants of Legionella pneumophila reveal that the Dot/Icm effector kinase LegK4 induces the host heat shock response via HSF1 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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