Hidden Chemical Tags on Proteins and RNA Team Up to Drive Inflammatory Bowel Disease
A new review in the Journal of Translational Medicine details how chemical tags on proteins and RNA interact to control ...
Tag: m6A methylation
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
RNA Tag METTL3 Drives Lung Scarring by Destabilizing a Key Fat-Droplet Protein
New research shows that the RNA methyltransferase METTL3 promotes lipid deposition and pulmonary fibrosis by destabilizing the messenger RNA of ...
Hypoxia Rewires RNA Methylation to Drive Pancreatic Neuroendocrine Tumor Growth
A new study reveals how low oxygen strips m6A methylation marks from tumor cell RNA, unleashing a signaling cascade that ...
Chemical Tags on Messenger RNA Steer the Plasticity of Pancreatic Alpha Cells
A new Nature Metabolism study shows that m6A methylation of messenger RNA actively controls the plasticity of pancreatic alpha cells, ...
Chemical Tags on mRNA Keep Pancreatic Alpha Cells From Turning Into Beta-Like Cells
New research shows that the mRNA modification m6A, installed by METTL14, is required to maintain pancreatic alpha-cell identity and prevent ...
Cold-Activated RNA Eraser Switches On Fat Burning Beyond UCP1
A new Nature Metabolism study shows that the cold-activated RNA demethylase ALKBH5 stabilizes CKB mRNA to drive UCP1-independent, creatine-based heat ...
METTL3 Emerges as a Molecular Hub Driving Tumor Immune Escape
A new review in the Journal of Translational Medicine details how the RNA methyltransferase METTL3 drives tumor immune escape through ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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