SPP1 emerges as a master switch shaping the tumor immune landscape
A new review details how the matrix protein SPP1 orchestrates immunosuppression across the tumor microenvironment and outlines emerging strategies to ...
Tag: lipid nanoparticles
Nanoparticle Geometry Boosts Antibiotic Power Against MRSA
Scientists have shown that tuning the internal nanoscale curvature of lipid nanoparticles can dramatically enhance the antibiotic daptomycin's ability to ...
Lactate Fuels a Deadly Feedback Loop That Drives Gut Damage in Ulcerative Colitis
A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...
Lipid Nanoparticles Deliver CAR Instructions to T Cells Without Viruses
Researchers have engineered a custom ionizable lipid nanoparticle that delivers CAR-encoding mRNA into human T cells with over 90 percent ...
mRNA Vaccine Paired With Radiotherapy Shrinks HER2-Positive Lung Tumors in Mice
A HER2-targeted mRNA lipid nanoparticle vaccine combined with fractionated radiotherapy suppressed tumor growth and reprogrammed the immune microenvironment in a ...
SUNY Invests $400,000 in Quantum Sensors, AI Cancer Diagnostics and Burn-Scanning Tech
SUNY Chancellor John B. King Jr. has announced $400,000 in Technology Accelerator Fund seed grants supporting nine faculty-led projects ranging ...
Computational Framework Ranks Safer RNA-LNP Formulations Before the Lab
Researchers at the University of Catania have built a modular computational framework that ranks RNA-lipid nanoparticle formulations for safety and ...
Rethinking Cancer Vaccine Carriers: A Bottleneck-First Test of Antigen Delivery Platforms
A new review in Materials Today Bio proposes a bottleneck-first framework for evaluating antigen delivery platforms in therapeutic cancer vaccines, ...
Camouflaged Nanoparticles Could Rewrite the Rules of Cancer Vaccines
A new review details how nanoparticles disguised with red blood cell membranes, exosomes, and synthetic coatings, loaded with personalized neoantigens, ...
Lipid Nanoparticle CAR Engineering Reveals Synergy Between T Cells and Macrophages Against Leukemia
A new study shows that lipid nanoparticle-delivered CAR mRNA engineers both human T cells and macrophages against CD19-positive leukemia cells, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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