Review Details Characterization Techniques for Lipid Nanotherapeutics
A 2025 review in Discover Pharmaceutical Sciences details the analytical techniques used to characterize lipid-based nanotherapeutics, covering physicochemical, chemical, and ...
Tag: lipid nanoparticles
Microneedle patch-based delivery of mRNA vaccines: opportunities for next-generation immunization
A comprehensive review details how microneedle patches integrate solid-state stabilization, skin-targeted delivery, programmable booster dosing, and on-patient optical documentation into ...
Treg-enriched delivery of ferrostatin-1 via anti-CD4/CD25 antibody-functionalized lipid nanoparticles to restore immune homeostasis in systemic lupus erythematosus
The study, published in Cellular & Molecular Biology Letters, introduces a lipid nanoparticle system loaded with ferrostatin-1 and functionalized with ...
Epigenome Editing Technologies Advance Toward Precision Gene Regulation and In Vivo Therapeutics
A comprehensive review details technological breakthroughs in epigenome editing platforms and highlights emerging in vivo strategies for disease modeling and ...
Overcoming Cellular Barriers: The Clinical Roadmap for Therapeutic CRISPR Gene Delivery
A comprehensive review of sixty-seven studies reveals that biological delivery barriers, rather than editing efficiency, determine the clinical success of ...
Engineered Hybrid Nanoparticles Improve Cardiac Delivery of Antifibrotic siRNA in Mice
Researchers designed hybrid nanoparticles combining reprogrammed macrophage nanovesicles and lipid carriers to direct therapeutic siRNA into damaged cardiac tissue while ...
Nanoparticles Reprogram Ascitic Macrophages into CAR Cells in Rodent Models
In rodent models and patient-derived ascites samples, lipid nanoparticles degraded TREM2 and reprogrammed tumour-associated macrophages into chimeric antigen receptor cells ...
Lipid nanoparticles get a pathway-matched blueprint for Alzheimer’s drug delivery
A new review proposes matching lipid nanoparticle designs to specific Alzheimer's disease pathways, from neuronal BACE1 siRNA delivery to microglia-targeted ...
Antihistamine-inspired lipid nanoparticles ferry mRNA and gene-editing tools into the brain
Researchers engineered lipid nanoparticles around the antihistamine hydroxyzine, achieving brain delivery of mRNA, CRISPR components and a radioprotective interleukin in ...
Cationic Lipid Nanoparticles Emerge as Versatile Delivery Platforms for Cancer Therapy
A new review examines how cationic lipid-based nanoparticles carry RNA, proteins and peptides into cancer cells, and why clinical translation ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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