mRNA Therapeutics Move Beyond Vaccines Into Cancer and Rare Disease Medicine
A new review details how mRNA therapeutics are expanding beyond infectious disease vaccines into cancer immunotherapy, protein replacement, autoimmune tolerance, ...
Tag: lipid nanoparticles
Microfluidic Method Boosts mRNA Vaccine Potency by Controlling Nanoparticle Architecture
A microfluidic technique that arranges metabolic and therapeutic RNAs in defined layers inside lipid nanoparticles raises ATP levels, boosts translation, ...
Pharmacokinetic Modeling Emerges as Key to Unlocking Nanoparticle Medicines
A new review argues that pharmacokinetic modeling frameworks such as PBPK, PopPK, and the proposed MIND workflow can bridge the ...
AI Is Rewriting How Nanoparticle Medicines Are Designed
A new Nature Reviews Bioengineering review details how machine learning is transforming nanoparticle drug delivery design, from formulation optimization and ...
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing Precise
A new review outlines how aptamer-guided nanocarriers could finally deliver CRISPR-Cas9 gene editing specifically to tumor cells, integrating molecular targeting, ...
Nanomedicines Offer New Routes Past the Brain’s Defenses Against Drug-Resistant Tumours
A new review in Molecular Cancer details how five classes of nanomaterials could breach the blood–brain barrier and dismantle the ...
Epigenetic Editing Offers Safer Route to Functional Hepatitis B Cure
A new review argues that programmable epigenetic editors could functionally cure chronic hepatitis B by durably silencing viral cccDNA and ...
Self-Assembling Carriers Could Redefine How Drugs Reach Their Targets
A new review in the Journal of Advanced Research details how self-assembling delivery platforms built from peptides, polyelectrolytes and natural ...
Nanomedicine Moves Beyond Drug Carriers Into Devices, Cells and Living Therapies
A new perspective in Biomedical Microdevices charts nanomedicine's evolution from passive drug carriers into implantable devices, engineered cells and living ...
Charge-Switching Lipids Make Lipid Nanoparticles Safer for Gene Delivery
Newly developed charge-switching S-lipids keep lipid nanoparticles neutral in circulation but cationic inside acidic endosomes, enabling nucleic acid delivery with ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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