Green Solvents Made From Natural Ingredients Could Transform Drug Delivery
A new review in the Journal of Nanoparticle Research details how natural deep eutectic solvents integrated into nanocarriers could deliver ...
Tag: lipid nanoparticles
Bigger Cargo, Better Design: Lipid Nanoparticles Rethought for Giant Gene Editors
A new Nature Biotechnology study shows that screening ionizable lipids with gene-editor-sized RNA cargo identified LC-1, a lipid nanoparticle formulation ...
New Lipid Nanoparticles Supercharge CRISPR Delivery of Bulky Gene-Editing RNA
Researchers at the University of Toronto engineered an ionizable lipid, LC-1, that preserves its fusogenic structure when loaded with large ...
AI framework designs mRNA vaccines that survive months without refrigeration
An AI framework called AGENT has engineered solid-state mRNA vaccines that retain full bioactivity after two months at 37 degrees ...
AI-Guided Design Yields mRNA Vaccines That Survive Months Without Refrigeration
MIT researchers used a data-efficient AI framework to discover solid-state mRNA–lipid nanoparticle vaccine formulations that retained full bioactivity after months ...
Training Immunity Against Variants That Do Not Yet Exist: A 600-Mutant Vaccine Strategy
A new mRNA vaccine strategy called Proactive Immune Training primes the immune system with one antigen and boosts it with ...
Threaded Microneedles Deliver mRNA and Drugs to Precise Skin Layers
A modular threaded microneedle system delivers a senescence-fighting hydrogel to the dermis and metabolism-restoring mRNA nanoparticles to subcutaneous fat, reversing ...
Smart Nanocarriers Aim to Outsmart Drug-Resistant Pneumonia
A new review in the Journal of Pharmaceutical Investigation details how targeted, stimuli-responsive, and immune-modulating nanocarriers could overcome lung barriers ...
Reprogramming Cells Inside the Body: The Regenerative Medicine Frontier Moving From Lab to Clinic
A new review in Advanced Science maps how in vivo direct reprogramming converts resident cells into functional replacements for damaged ...
Ribonucleotides Supercharge Cancer Chemotherapy Through Mitochondrial DNA Stress
Researchers found that the natural nucleotide CMP dramatically amplifies floxuridine-driven cGAS–STING antitumor immunity and packaged the pair into nanoparticles that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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