FDA-Approved RNA Drugs Show Mostly Mild Side Effects, But Long-Term Safety Data Remain Thin
A new cross-platform review of eighteen FDA-approved RNA therapeutics finds that adverse effects depend more on delivery chemistry and administration ...
Tag: lipid nanoparticles
In vivo CAR-T therapy aims to turn bespoke living drugs into universal genetic medicines
A new review charts how in vivo CAR-T engineering could transform customized living drugs into scalable, off-the-shelf genetic medicines.
Nanoparticles may carry CRISPR gene editing into infant neuroblastoma
Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...
Nanoparticles That Help Cells Remember: A New Bid to Make mRNA Therapies Last Longer
A new hypothesis proposes that programmable lipid nanoparticles may shape cellular memory systems to extend the durability of mRNA vaccines ...
Head-to-Head Comparison Reveals mRNA Vaccines Behave Differently in Human Blood
Australian researchers have completed the first head-to-head comparison of three mRNA-lipid nanoparticle vaccine platforms in human blood, revealing key differences ...
Redesigned lipid nanoparticles steer mRNA away from the liver and toward target tissues
Researchers redesigned lipid nanoparticles to cut liver accumulation of locally injected mRNA by up to eighty-fold in mice while preserving ...
Tiny Capsules, Big Promise: How Nanoencapsulation Is Unlocking Plant Medicine
A new review details how micro- and nanoencapsulation technologies are overcoming the poor stability, solubility, and bioavailability of plant-derived bioactive ...
Placental Hormone GDF15 Emerges as Key Driver of Fetal Growth and Potential Therapy
New research in mice and pigs shows that the placental hormone GDF15 drives fetal growth by activating a STAT3-IGF2 signaling ...
Lipid Nanoparticles Reprogram NK Cells Inside the Body to Fight Cancer and Autoimmune Disease
MIT engineers have developed lipid nanoparticles that reprogram natural killer cells inside the body to destroy cancerous and autoreactive T ...
Lipid nanoparticles reprogram natural killer cells inside the body to fight cancer
MIT researchers have engineered ligand-directed lipid nanoparticles that reprogram natural killer cells into CAR-bearing cancer killers directly inside living animals, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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