Recombinant HPV16 E7 vaccine plus CD137 agonism clears tumors in mice
A recombinant overlapping peptide vaccine targeting HPV16 E7, combined with 4-1BB agonist antibody, eradicated established tumors in most treated mice ...
Tag: iScience
New genetic switch lets scientists steer two cell types independently
Researchers at Japan's National Institute of Genetics developed an orthogonal Cro/OR3 gene expression system that, combined with Gal4/UAS, independently controls ...
Your Sense of Time Stretches as You Learn to Reach Faster
As people practiced rapid hand-reaching movements, their perception of brief visual durations stretched progressively, and the stretching tracked how much ...
Baleen records reveal how marine heatwaves drained humpback whale energy and reproduction
A University of Hawai'i-led study of baleen chemistry from stranded female humpbacks shows that the 2014–2016 marine heatwave forced whales ...
New Pathway Identified in Keloid Formation
Researchers identify the CD147-CENPF signaling pathway as a key driver of keloid formation, offering a new target for treating this ...
Smartwatch Data Reveal Heart Rhythm Shifts Days Before Chronic Pain Is Diagnosed After Surgery
A study of NIH All of Us participants found that wearable heart rate rhythms and waketimes shifted in the days ...
Tiny Tumor Fragments From Needle Biopsies Predict Which Breast Cancer Drugs Will Work
Patient-derived microtumors grown from core needle biopsies as small as a few cubic millimeters of tissue successfully predicted breast cancer ...
Ancient somatosensory circuit architectures employ flexible molecular strategies
A study of little skate embryos reveals that the layered spinal cord and target-dependent maturation of touch and pain circuits ...
Training Program Helps Oncology Nurses Master End-of-Life Care Skills
A structured seven-week education program at Peking University Cancer Hospital significantly improved oncology nurses' knowledge of and attitudes toward end-of-life ...
Time Spent Close to Cats, Not Ownership Itself, Boosts Owner Mood
A Kyoto University study of 29 cats and 19 owners found that owners' positive moods correlate with daily physical closeness ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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