Iron-Scavenging Machinery Reveals a Hidden Route to Tuberculosis Drug Resistance
A new study reveals that the MarR family regulator AcasR controls mycobacterial susceptibility to the anti-tuberculosis compound ACA by repressing ...
Tag: Iron homeostasis
Grape Seed Compound Shows Promise Against Gluten-Induced Gut Cell Stress
A grape seed-derived polyphenol may protect the intestinal lining from a notorious gluten peptide, according to new research published in ...
Plant receptor SRF3 balances iron uptake and immune defense, study finds
Salk Institute scientists discovered that the plant cell surface receptor SRF3 coordinates iron homeostasis and immune responses through ubiquitin-dependent reorganization, ...
Iron’s Dark Side: How Ferroptosis Drives Brain Disease and What Could Stop It
A new review proposes the Iron-Brain Nexus framework to explain why the brain is uniquely vulnerable to iron-dependent ferroptotic cell ...
Ancient Skullcap Flavonoid Supercharges Last-Resort Antibiotic Against Deadly Hospital Superbug
A new in vitro study shows that baicalein, a flavonoid from Scutellaria baicalensis, synergizes with ceftazidime-avibactam to kill carbapenem-resistant Acinetobacter ...
Iron-Sensing Protein Revealed as Master Switch for Aflatoxin Production in Crop Fungus
Researchers have identified the bZIP transcription factor AflHapX as the molecular link between iron availability and aflatoxin B1 production in ...
Iron’s Master Switch: How Cells and the Body Keep the Perfect Balance
A new review maps the molecular circuits, from intracellular IRE-IRP sensors to the liver hormone hepcidin, that keep the body's ...
A Methylation Signature in Brain Fluid Predicts Who Survives a Deadly Stroke
Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...
Kale Nanovesicles Boost Cancer Drug’s Kill Switch in Liver Tumor Cells
Researchers at Yeditepe University report that kale-derived exosome-like nanovesicles combined with the dual PI3K/mTOR inhibitor dactolisib trigger apoptosis and alter ...
Electroacupuncture Meets a Smart Hydrogel to Rebuild Injured Spinal Cords
A conductive, antioxidant hydrogel loaded with stem cells and paired with electroacupuncture suppressed ferroptosis and restored motor function in mice ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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