Genetic Study Links Iron-Cell Death Genes to Leukemia Risk via Immune Cells
A Mendelian randomization study finds that ferroptosis-related genes influence acute myeloid leukemia risk directly and indirectly through specific immune cell ...
Tag: iron-dependent cell death
Ferroptosis emerges as a central vulnerability in digestive system cancers
A narrative review links iron-dependent ferroptosis to tumor progression and therapy response in digestive system cancers, while flagging major barriers ...
Astragaloside IV Emerges as a Candidate Ferroptosis Link in Heart Hypertrophy
Astragaloside IV reduces pathological cardiac hypertrophy and suppresses ferroptosis in separate models, but direct experiments are needed to establish whether ...
Turning Off a Cancer Cell’s Survival Switch: How NRF2 Controls Ferroptosis in Targeted Therapy
A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...
Gut Microbe Molecule 7-KDCA Shields Diabetic Muscles by Blocking NLRP1-Ferroptosis Cell Death
Researchers found that the gut bacterial metabolite 7-KDCA protects against diabetic muscle wasting by suppressing NLRP1 inflammasome activation and ferroptosis ...
Iron, Lipids and Cell Death: Ferroptosis Biomarkers Emerge as Clues to Vitiligo Activity
A new case-control study finds that serum markers of ferroptosis, including ACSL4, MDA and ROS, are elevated in vitiligo vulgaris ...
Copper Overload Silences a Key Liver Fat Gene, Pushing Cells Into Ferroptosis in Wilson Disease
New research shows that copper accumulation in Wilson disease shuts down the PPARα–FABP1 fat-handling axis in hepatocytes, sensitizing them to ...
Iron, Inflammation, and a Deadly Paradox: Rethinking Cancer Wasting Through Ferroptosis
A new iScience review argues that ferroptosis, an iron-driven form of cell death, links tumor and immune signals to muscle ...
Chemical Tags on RNA Hold the Switch That Decides Whether Cells Die of Iron
A comprehensive review maps how m6A RNA methylation regulates ferroptosis across cancer, cardiovascular, neurological and metabolic diseases, revealing new therapeutic ...
Cellular Death Switch Found: Fission Protein MFF Senses and Drives Ferroptosis
Researchers have identified mitochondrial fission factor as a phosphorylation-controlled switch that senses and drives ferroptosis, built a live-cell biosensor to ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!