Inside the Cell’s Sugar Delivery System: Scientists Map How GLUT4 Reaches the Membrane
A new systematic review of 350 studies maps the complete molecular machinery that moves the GLUT4 glucose transporter to the ...
Tag: insulin signaling
Alcohol Rewires the Brain’s Insulin and Notch Signals to Strip Away White Matter
A new postmortem study reveals that alcohol use disorder disrupts insulin, IGF, and Notch signaling in frontal lobe white matter, ...
Insulin Reshapes the Brain’s Ciliated Gatekeepers, Study Finds
New research shows that prolonged insulin exposure remodels the multiciliated epithelial cells of the choroid plexus by expanding the multiciliated ...
Fat Body Hormone SPARC Drives Insulin Release and Body Growth in Fly Larvae
A new BMC Biology study identifies the fat body-secreted matricellular protein SPARC as an evolutionarily conserved, incretin-like signal that promotes ...
Zebrafish Reveal a Surprising Trick for Rebuilding Nerves: Letting Dendrites Go First
New research in adult zebrafish shows that transient dendritic pruning driven by repressed mTORC1 signaling is essential for efficient axonal ...
Diabetes Drugs May Boost Survival After Brain Injury Surgery, Study Suggests
A new study in Neurocritical Care links GLP-1 receptor agonist use to improved survival in patients undergoing surgery for traumatic ...
Hemp Seed Cake Yields Two Natural Molecules That Block a Key Diabetes Enzyme
Scientists isolated two phenylpropionamide compounds from hemp seed cake that inhibit the diabetes-linked enzyme PTP1B in vitro, with kinetic, docking, ...
Phosphatases Emerge as Promising Targets Against Diabetic Kidney Disease
A comprehensive review argues that classical protein tyrosine phosphatases, long considered undruggable, are central drivers of diabetic kidney disease and ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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