Higher HLA Epitope Mismatch Links to Innate Immune Skewing in Liver Transplants
A translational study reveals that higher predicted donor-recipient HLA epitope mismatch associates with distinct innate immune cell configurations in clinically ...
Tag: innate immunity
Dengue Virus Evades Innate Antiviral Defenses as Dysregulated Death Pathways Drive Severe Pathology
A comprehensive literature review reveals how dengue virus evades host pattern recognition receptors and manipulates cell death pathways to cause ...
Review Links ADAR RNA Editing Dysregulation to Multiple CNS Disorders
A review in Cellular & Molecular Biology Letters examines how ADAR-mediated RNA editing dysregulation contributes to pathogenesis in various central ...
IPEC-J2 Cells Recapitulate Key Pathway Responses to PEDV Infection in Piglet Jejunum
A cross-model transcriptomic study shows IPEC-J2 cells share core immune pathways with PEDV-infected piglet jejunum despite differences in response magnitude.
Review details phosphoantigen and butyrophilin T cell mechanisms
A review in Genes & Immunity details the mechanisms by which phosphoantigens and butyrophilins activate γ9δ2 T cells, highlighting structural ...
TLR8 Inhibition Targets Liver Fibrosis in Biliary Atresia
A new study demonstrates that blocking TLR8 signaling reduces liver inflammation and fibrosis in biliary atresia models, identifying a potential ...
ZBP1 identified as key inflammatory sensor in allergic rhinitis
A new single-cell atlas identifies ZBP1 as a critical inflammatory sensor in the nasal mucosa of allergic rhinitis patients, linking ...
AI Model Distinguishes SLE Immune Profiles from Healthy Controls
An AI model perfectly distinguished SLE patients from healthy controls by identifying specific immune cell profiles associated with active humoral ...
Why Bed Bugs Do Not Transmit Infectious Diseases Despite Harboring Pathogens
A systematic review indicates that bed bugs fail to transmit infectious diseases to humans due to a cumulative series of ...
Bovine ADAM9 Variant Linked to Immune Response Differences
A study in BMC Veterinary Research identifies a bovine ADAM9 genetic variant that alters neutrophil responses to bacterial stimuli, affecting ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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