Pig-Killing Virus Unmasked: One Protein Quietly Disables Two Cellular Alarm Systems
New research shows the African swine fever virus protein QP509L suppresses innate immunity by simultaneously blocking STING trafficking and STAT1-dependent ...
Tag: innate immunity
Hidden Sugar Signals on Pig Organs May Decide Xenotransplant Success
A new review argues that sugar-based signaling through Siglec receptors and complement Factor H forms a hidden regulatory layer determining ...
Master Switch PRDM1 Steers Natural Killer Cell Maturation and Cancer Defense
A new review details how the transcriptional repressor PRDM1 orchestrates natural killer cell maturation, effector function, and tumor suppression, with ...
Acne Drug Isotretinoin Calms Inflammation at Gene and Blood Levels, Study Finds
New research shows oral isotretinoin suppresses five key pro-inflammatory cytokines at both gene and protein levels in acne patients, with ...
Insect Immune Genes Reveal How a Tiny Psyllid Spreads Devastating Crop Disease
Researchers have catalogued the Toll immune pathway genes of the potato psyllid and shown that the insect mounts haplotype-specific responses ...
Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts ...
Damaged Mitochondrial DNA Emerges as a Central Driver of Pulmonary Arterial Hypertension
A new review argues that oxidized mitochondrial DNA acts as both a persistent inflammatory signal and a potential biomarker driving ...
Neutrophils Fail Quietly in Multiple Myeloma Even When Counts Look Normal
A study of Zambian multiple myeloma patients shows their neutrophils have severely impaired phagocytosis and oxidative burst despite normal blood ...
RNA Sensor MDA5 Emerges as a Surprising Ally of Tumors Against Immune Attack
New research in Nature Communications shows that the viral RNA sensor MDA5 helps tumors evade immunity, and that disabling it ...
After Sepsis, Macrophages Fall Silent: Mouse Study Maps the Immune Collapse Behind Deadly Secondary Pneumonia
A two-hit mouse model reveals that sepsis leaves macrophages functionally silenced, blunting lung cytokine and chemokine responses to secondary Pseudomonas ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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