Rare Parkinson’s Case Reveals Platelet Molecular Changes Linked to Disease Progression
A study of a rare early-onset Parkinson's disease case reveals that molecular changes in platelets track disease progression more clearly ...
Tag: inflammation regulation
Review Highlights Mushroom Compounds Regulating NF-κB for Immune and Cancer Therapies
A scientific review highlights how mushroom-derived bioactive compounds regulate the NF-κB pathway to influence immune response and cancer progression.
Entamoeba Clones Trigger Divergent Liver Immune Trajectories in Murine Infection Model
Time-resolved transcriptome analyses in mice reveal that pathogenic and non-pathogenic Entamoeba histolytica clones trigger distinct hepatic immune trajectories differing in ...
Surface Y RNAs Turn Monocytes into Inflammatory Amplifiers
Researchers report that Y RNAs on the surface of human monocytes bind extracellular histones and amplify TLR2/TLR4-driven inflammatory signaling, with ...
Immune Enzyme PTPN2 Emerges as Master Switch in Sepsis Inflammation
McGill University researchers have identified the enzyme PTPN2 as a key regulator of non-canonical inflammasome activation, revealing how it shapes ...
Ancient Chinese Herb Yields a Polysaccharide That Kills Staph and Calms Runaway Inflammation
A fructan polysaccharide from the traditional Chinese herb Polygonatum kingianum killed Staphylococcus aureus, eradicated mature biofilms, and restored balanced immune ...
A single ubiquitin enzyme emerges as a master switch between liver repair and liver destruction in MASH
Researchers report that loss of the K63-linked ubiquitination enzyme UBE2N in hepatocytes drives metabolic dysfunction-associated steatohepatitis by blocking p62-mediated mitophagy ...
Virus-like particles enable targeted gene engineering, pooled CRISPR screens in myeloid cells
Primary human myeloid cells are emerging as important components of next-generation immunotherapies, but they have traditionally been difficult to engineer ...
All-Trans Retinoic Acid Suppresses Severe Fever With Thrombocytopenia Virus Inflammation in Mice
Severe fever with thrombocytopenia syndrome (SFTS), driven by SFTS virus, can trigger life-threatening systemic inflammation, yet targeted host-directed therapies have ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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