Meningioma Study Points to CD73 as a Candidate Biomarker of Tumor Grade
An exploratory Brazilian study of 40 surgically resected meningiomas found that CD73 expression rises while PD-L1 falls in WHO grade ...
Tag: Immunotherapy
Immunotherapy Before Surgery: Sintilimab Helps Shrink Advanced Ovarian Cancer in Landmark Case
A case report describes advanced ovarian cancer shrinking dramatically after the PD-1 inhibitor sintilimab was added to chemotherapy, enabling complete ...
Hidden RNA Tags May Steer Lung Cancer Growth, Treatment Response, and Survival
A sweeping review reveals how the RNA modification N6-methyladenosine orchestrates lung cancer progression, drug resistance, immunotherapy response, and survival prediction.
Cancer Immunotherapy Triggered a Heart Attack in One Patient—Here’s What It Reveals
A new case report describes a 70-year-old lung cancer patient with no cardiovascular risk factors who suffered a massive heart ...
Chemotherapy Preconditioning Fails to Boost Inhaled IL-15 Immunotherapy in Dogs with Lung Metastases
A UC Davis clinical trial found that doxorubicin lymphodepletion before inhaled interleukin-15 therapy did not improve response rates in dogs ...
How Immunotherapy Is Rewriting the Rules of Liver Cancer Treatment
A sweeping review details how immune checkpoint inhibitors, combination regimens, CAR-T cells, vaccines, and oncolytic viruses are transforming treatment of ...
Chemotherapy-Free Drug Combo Shows Promise for Early Triple-Negative Breast Cancer
A phase II trial found that neoadjuvant camrelizumab plus apatinib, a chemotherapy-free combination of immunotherapy and anti-angiogenic therapy, produced manageable ...
Dual-Target CAR-T Cells Outsmart Antigen Shedding in Ovarian Cancer
Researchers have engineered biparatopic CAR-T cells that target both full-length MUC1 and the truncated MUC1β stub exposed after MUC1α shedding, ...
Immune Checkpoint Blockers Linked to Rare Blood Platelet Disorder in Two Global Drug Safety Databases
A pharmacovigilance analysis of US and Japanese adverse event databases finds that PD-1 and PD-L1 checkpoint inhibitors show a robust, ...
Molecular Path Cleansers: Enzymes That Strip Tumor Defenses to Boost Immunotherapy
A new review details how enzymes that degrade the extracellular matrix and glycocalyx could open solid tumors to immune attack, ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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