Personalized Neoantigen Vaccine Turns a Patient’s Immune System Into a TCR Discovery Engine
A personalized dendritic cell neoantigen vaccine given to an ovarian cancer patient enabled Swiss researchers to track expanding T-cell clonotypes ...
Tag: Immunotherapy
PD-1 and LAG-3 Double-Positive T Cells Predict Better Gastric Cancer Survival
A multicohort study finds that gastric tumors rich in PD-1 and LAG-3 double-positive CD8 T cells—an activated, pre-exhausted population—are linked ...
Natural Killer Cells Stay Battle-Ready in Obesity-Linked Cancer Terrain
Researchers at Trinity College Dublin report that KHYG-1 natural killer cells retain their cancer-killing function after exposure to the tumour ...
Scientists Decode Colorectal Tumors With Imaging and Multi-Omics Fusion
A new review in the Journal of Translational Medicine maps how radiomics, pathomics and multi-omics integration can decode the tumor ...
Second CAR T-Cell Infusion Hits Myeloma After CELMoD Bridging
A German case report describes rapid deep response to ciltacabtagene autoleucel as a second BCMA-directed CAR T-cell therapy after mezigdomide-based ...
Scientists Map How Tumours Push Immune Cells Into Exhaustion
A review in Experimental & Molecular Medicine examines how chronic antigen exposure and a hostile tumour microenvironment reprogram T cells ...
China’s Cancer Research Shifts From Molecular Reductionism to Holistic Integrative Medicine
A new review maps how Chinese cancer research has evolved from single-target molecular reductionism toward a three-tier holistic integrative medicine ...
Engineered Herpes Viruses Show Modest but Meaningful Gains Against Solid Tumors
A meta-analysis of 38 clinical trials finds oncolytic herpes simplex virus therapy delivers modest anti-tumor activity across solid tumors, with ...
AI-Powered Cancer Drug Research Has Exploded Since 2018, Landmark 15,554-Study Analysis Reveals
A bibliometric analysis of 15,554 publications maps the explosive growth, global leaders, and future challenges of AI-driven anticancer drug design ...
Immune Checkpoint BTLA Emerges as Surprising Prognostic Marker in Ovarian Cancer
A multi-omics study identifies the immune checkpoint molecule BTLA as significantly upregulated in ovarian cancer and associated with favorable overall ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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