SMARCAL1 condensates drive radioresistance and immunosuppression in tumours
A new study shows that SMARCAL1 forms nuclear condensates that reprogram chromatin and methionine metabolism, weakening radiotherapy and immunotherapy responses.
Tag: Immunotherapy
TAM receptors and STAT–SOCS signaling shape the immune landscape of thymic epithelial tumors
A new integrative analysis links TAM receptor and STAT–SOCS signaling to immune infiltration patterns in thymic epithelial tumors.
DNA repair gene mutations flag better immunotherapy responses in FH-deficient kidney cancer
A multicenter study found that FH-deficient kidney cancer patients with DNA damage repair gene mutations showed significantly higher response rates ...
Blocking One Prolactin Receptor Isoform Selectively Disarms Lupus Immune Cells
Researchers report that a splice-modulating oligomer that reduces the long prolactin receptor isoform lowered pathogenic immune signatures in lupus patients' ...
Cancer Cells Steal Mitochondria From Immune Cells to Survive and Evade Therapy
A new review details how tumor cells import, export and steal mitochondria through nanotubes and vesicles to fuel growth, exhaust ...
TGF-β signaling symposium reveals new paths from development to cancer therapy
Researchers meeting in Nanchang reported new mechanisms of TGF-β signaling in stem cell differentiation, cancer, fibrosis and immunity, alongside inhibitors ...
CAR-NK Cells Engineered to Intercept Breast Cancer Metastasis
A new review in Breast Cancer Research outlines a framework for engineering CAR-NK cells to intercept circulating tumor cells, target ...
Surgeons remove thymoma and a woman’s stiff-person syndrome improves
A case report describes a 60-year-old woman with thymoma-associated stiff-person syndrome who walked independently again two years after extended thymectomy ...
CD276 Blockade Slows Gastric Cancer and Boosts Anti-PD-1 Immunotherapy in Preclinical Study
Blocking the CD276 molecule slowed gastric cancer growth and, combined with anti-PD-1 therapy, produced the strongest tumor suppression and increased ...
Engineered NK Cells Target CD73 to Attack Hard-to-Treat Lung Adenocarcinoma
Preclinical research shows that natural killer cells engineered with a CD73-targeting receptor kill relapsed or refractory lung adenocarcinoma cells in ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!