Cancer Cells Steal Mitochondria From Immune Cells to Survive and Evade Therapy
A new review details how tumor cells import, export and steal mitochondria through nanotubes and vesicles to fuel growth, exhaust ...
Tag: Immunotherapy
TGF-β signaling symposium reveals new paths from development to cancer therapy
Researchers meeting in Nanchang reported new mechanisms of TGF-β signaling in stem cell differentiation, cancer, fibrosis and immunity, alongside inhibitors ...
CAR-NK Cells Engineered to Intercept Breast Cancer Metastasis
A new review in Breast Cancer Research outlines a framework for engineering CAR-NK cells to intercept circulating tumor cells, target ...
Surgeons remove thymoma and a woman’s stiff-person syndrome improves
A case report describes a 60-year-old woman with thymoma-associated stiff-person syndrome who walked independently again two years after extended thymectomy ...
CD276 Blockade Slows Gastric Cancer and Boosts Anti-PD-1 Immunotherapy in Preclinical Study
Blocking the CD276 molecule slowed gastric cancer growth and, combined with anti-PD-1 therapy, produced the strongest tumor suppression and increased ...
Engineered NK Cells Target CD73 to Attack Hard-to-Treat Lung Adenocarcinoma
Preclinical research shows that natural killer cells engineered with a CD73-targeting receptor kill relapsed or refractory lung adenocarcinoma cells in ...
BTK Inhibitor Plus Immunotherapy Shows Durable Responses in Relapsed CNS Lymphoma
A prospective phase II trial reports that orelabrutinib combined with sintilimab achieved a 60.7 percent response rate and a median ...
Serine Supplements Boost T Cell Attack on Tumors in Preclinical Models
Preclinical research shows serine supplementation, rather than restriction, suppresses tumor growth and reinvigorates CD8+ T cells by countering tumor cell ...
French Bulldog Brain Tumors Show Distinct Gene Expression From Related Breeds
RNA sequencing of 18 canine brain tumors reveals 45 genes expressed at different levels in French bulldogs compared with boxers ...
Engineered IL-6-Responsive CAR Macrophages Boost CAR-T Cell Activity Against Solid Tumors
Engineered IL-6-responsive CAR macrophages enhanced CAR-T cell antitumor activity, matrix remodeling, and survival in preclinical solid tumor models.
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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