Cellular Nibbling: How Trogocytosis Shapes Immunity, Cancer, and Infection
A new review examines how trogocytosis, the process by which cells nibble membrane fragments from one another, shapes immune regulation, ...
Tag: immune regulation
Hidden Immune Brake Found to Keep Gut Inflammation in Check
Researchers report that the transcription factor Zbtb44, through SUMOylation-dependent interaction with T-bet, represses interferon-gamma production by T cells and thereby ...
How wandering gut T cells drive disease far beyond the intestine
A sweeping review explains how the molecular machinery that guides intestinal T-cell migration links gut inflammation, cancer immune evasion, and ...
Machine Learning Maps How Environment and Immunity Shape Childhood Eczema Risk
A machine learning analysis of 217 South African AmaXhosa children has identified one protective and two susceptibility clusters linking rural ...
Biodiversity and Asthma: What a Major Meta-Analysis Really Found
A new meta-analysis in Nature Communications finds that environmental bacterial richness shows a significant protective association with asthma, while vegetation ...
Plateau Fish Rewire Their Immune Systems to Survive Oxygen Starvation
A new genomic study reveals that the Tibetan plateau fish Gymnocypris eckloni deploys distinct immune strategies against severe short-term and ...
High-Altitude Holsteins Reveal a Hidden RNA Code Behind Hypoxia Tolerance
A new transcriptomic study of Holstein cows reveals thousands of messenger and long non-coding RNAs shifting with altitude, pointing to ...
Cell Study Reveals How TRIM28 Fires Up Inflammatory Macrophages to Drive Keratinocyte Overgrowth
New laboratory research shows that the protein TRIM28 drives macrophages toward a pro-inflammatory state through the NLRP3/SGT1 axis and SUMOylation, ...
Macrophages move captured proteins onto their own surface during live-cell uptake
New research shows that macrophages can transfer functionally active proteins from engulfed live cells onto their own surface rather than ...
Cryo-EM Reveals How ATP Switches Off the Human NLRP6 Inflammasome
Cryo-EM structures of human NLRP6 in ATP-bound and unbound conformations reveal how ATP serves as an endogenous inhibitor of inflammasome ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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