Hippocampus encodes experience as disentangled variables in cell assemblies
A study in behaving mice reports that the hippocampus encodes different aspects of experience as disentangled variables in cell assemblies, ...
Tag: hippocampus
Research report: In vivo blood and ex vivo brain solid-phase microextraction coupled with LC-MS/MS for mapping unbound cannabidiol, phase I metabolites, and endocannabinoid tone
A solid-phase microextraction and LC-MS/MS platform has, for the first time, tracked unbound cannabidiol in the living bloodstream and mapped ...
Cerebellar Degeneration Impairs Feedback-Based Learning and Control
A new study reveals that cerebellar degeneration impairs feedback-based learning and inhibitory control, with structural changes in the hippocampus and ...
High-Salt Diet Impairs Memory in Aged Mice by Overwhelming Mitochondrial Cleanup
A two-month high-salt diet impaired learning and memory in aged male mice and increased amyloid-beta accumulation, activating a PINK1/Parkin mitophagy ...
CD51 defines specialized astrocyte roles in mouse brain circuits
A mouse study shows that CD51-positive and CD51-negative astrocytes have distinct roles in synapse formation, memory-circuit adaptation and recovery from ...
Unstable Regulatory T Cells Weaken the Blood–Brain Barrier After Surgery
A study in Cell Death Discovery links perioperative destabilization of regulatory T cells to blood–brain barrier disruption through a β-catenin–tight ...
Vitamin D Emerges as Possible Bridge Between Neuropathic Pain and Brain Fog
A new narrative review maps how vitamin D deficiency may sit at the mechanistic crossroads of neuropathic pain and cognitive ...
Loneliness linked to smaller brain memory regions when Alzheimer’s biomarker is elevated
A large IGNITE study of cognitively unimpaired older adults found that loneliness was associated with smaller CA3 and entorhinal cortex ...
SIK1–NR4A2 pathway linked to excitability in rat epilepsy model
Machine-learning screening and experiments in rats and cultured neurons identified SIK1 as a regulator of seizure severity and neuronal excitability ...
Angelman syndrome mice show disrupted Kv4.2 channel redistribution
A mouse study links loss of UBE3A to impaired Kv4.2–DPP6 complex remodeling and weakened dendritic channel gradients associated with excitability ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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