New Spatial Genomics Method SpaceA Reveals 3D Genome Architecture in Mouse Embryos
A new spatial 3D genomics technology called SpaceA maps long-range chromatin interactions inside intact mouse embryo tissue and uncovers a ...
Tag: heterochromatin
Hidden Chromatin Domains Emerge When Scientists Watch Single Chromosomes Fold
Single-molecule chromatin tracing in C. elegans embryos has revealed three distinct classes of megabase-scale heterochromatin domains, including condensin-dependent TAD-like structures ...
Mosquito Genomes Hide Dramatic Diversity Behind Identical Chromosome Counts
New cytogenetic and flow cytometry research shows that three Neotropical mosquito species with identical chromosome numbers harbor dramatically different genome ...
African swine fever virus reshapes host genome architecture within hours of infection
New research shows that African swine fever virus extensively reorganizes host chromatin architecture and RNA polymerase II activity within hours ...
Open Chromatin Is Not So Open: Active Genes Ride on Condensed Domains
New simulations reveal that euchromatin is mostly condensed into dense domains, with short active regulatory regions protruding on their surfaces ...
Stress Sensor Reveals How Malaria Parasites Switch to Transmission Mode
Researchers have identified the transcription factor AP2-HS and a GDV1–antisense RNA feedback loop as the mechanism by which malaria parasites ...
SIRT1 Silences Jumping Genes by Stabilizing Heterochromatin Complexes
Researchers report that SIRT1 suppresses L1 retrotransposon activity by recruiting and stabilizing the heterochromatin factors Lamin B1 and KAP1, an ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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