Mitapivat Supercharges ATP Export in Healthy Red Blood Cells but Leaves Sickle Cells Unmoved
A new ex vivo study shows the pyruvate kinase activator mitapivat raises intracellular and exported ATP in healthy red blood ...
Tag: glycolysis
Cancer Cells Run on a Metabolic Hybrid Engine, and Surgeons May Soon Map It
A new review argues that cancer cells toggle between glycolysis and mitochondrial respiration in hybrid metabolic states, and that mapping ...
Tiny RNA Molecule May Explain Why Some People Resist Tuberculosis Infection
A new PLOS Pathogens study finds that the microRNA-1246 regulates macrophage lipid metabolism and helps explain why some household contacts ...
Sugar Molecules, Not Size, Keep Key Metabolic Enzyme Working Under Stress
A new study shows that sugar-based chemical interactions, rather than molecular crowding size, help the glycolytic enzyme PFKP stay active ...
Sticky Nanosheets Deliver Sustained Hydrogen to Rejuvenate Aging Testes in Mice
Researchers have developed a bioadhesive nanoplatform that releases hydrogen slowly inside the scrotum, restoring sperm production in aged mice by ...
Onion Extract and Diabetes Drug Show Promise Against Common Gut Parasite in Lab Study
Egyptian researchers found that metronidazole, metformin, and onion extract all suppress Blastocystis growth in lab cultures by disrupting the parasite's ...
How Exercise Reprograms Glucose Metabolism to Fight Osteoporosis
A new review reveals that exercise protects against osteoporosis by reprogramming how bone cells burn glucose, linking glycolysis, lactate signaling, ...
Lab-Grown Retinas Mirror the Real Thing, but Their Metabolism Lags Behind
A new metabolomic study shows that mouse retinal organoids share 148 of 166 detected metabolites with native retina, yet reveal ...
Lactate emerges as both warning sign and driver of kidney injury after heart surgery
A new iScience study combining machine learning on over 6,500 patient records with rat and cell experiments shows that lactate ...
Newborns with congenital diaphragmatic hernia show hyperactive but inefficient mitochondria in endothelial cells
Endothelial cells from newborns with congenital diaphragmatic hernia display hyperactive but inefficient mitochondria, linking cellular energy dysfunction to pulmonary vascular ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!