How Cells Choose Between DNA Repair Pathways—and Why It Matters for Cancer
A new review explains how the contest between BRCA1-BARD1 and the 53BP1 axis at DNA break ends determines whether cells ...
Tag: genome stability
Loss of Checkpoint Kinase 2 Reshapes How Cells Repair Broken DNA
A new Cell Death & Discovery study shows that checkpoint kinase 2 deficiency alters how cells engage homologous recombination and ...
ATRX partners with 9-1-1 and CST to protect genome replication and telomeres
Every time a human cell divides, it must copy roughly six billion letters of DNA—a feat accomplished by molecular machines ...
Archaeal NurA Nuclease Structure Reveals Catalysis and Cooperation in DNA Break Repair
DNA double-strand breaks are among the most dangerous forms of genetic damage a cell can experience. When both strands of ...
DNA Repair Mechanisms Show Preference for Certain Genetic Damage
A wound that heals imperfectly leaves a scar. In the genome, the equivalent scar is a mutation: a permanent alteration ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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