Tag: Genome editing

A new review details how marker-free transformation and CRISPR-based clean gene technology could deliver safer, more acceptable genetic improvements in ...

Researchers at the University of Toronto engineered an ionizable lipid, LC-1, that preserves its fusogenic structure when loaded with large ...

Multiplex CRISPR-Cas9 editing of twelve flowering-time repressors has produced soybean lines that flower up to four weeks earlier under controlled ...

Researchers transformed the inactive compact nuclease CgCas12n into a high-efficiency genome and base editor through arginine enrichment and guide RNA ...

Ultra-accurate targeted long-read sequencing of genome-edited zebrafish reveals widespread CRISPR-Cas9 mosaicism, with structural variants and off-target mutations inherited into the ...

A new Nature Plants commentary argues that the fate of CRISPR genome-edited crops depends less on molecular biology than on ...

A new review traces how CRISPR genome editing has evolved from blunt molecular scissors into increasingly precise therapeutic tools for ...

Researchers have identified a distal IRF4 chromatin regulatory element as the genomic control point that permits inflammation-induced reprogramming of human ...

A new prime editing-based strategy called prime assembly enables precise integration of large DNA fragments and programmable genomic rearrangements without ...

Researchers reprogrammed the native CRISPR-Cas system of a commercial probiotic bacterium to permanently disable its tetracycline resistance gene while preserving ...