Free-Base Editing Delivers Cleaner DNA Changes in Crops
A modular cytidine base editor that separates its Cas9 nickase and deaminase produced fewer unwanted DNA changes in moss and ...
Tag: Genome editing
Agrobacterium’s Own T-DNA Powers Simple One-Step Genome Editing
Chinese researchers have developed a one-step genome editing method for Agrobacterium that uses the bacterium's own induced T-DNA as a ...
CAR-T Cell Therapy Faces Its Next Test: Solid Tumours, Safer Designs and Lower Costs
A comprehensive review maps the engineering, biomarker, manufacturing and economic innovations that will determine whether CAR-T cell therapy can move ...
Zebrafish Genetic Engineering Enters a New Era of Precision Gene Control
A new review charts how zebrafish genetic engineering has evolved from random chemical mutagenesis to precise, reversible CRISPR-based gene control ...
CRISPR frame-restoring edit revives lost tomato gene and boosts fruit nutrition
Researchers used a temperature-tolerant LbCas12a genome editing system to restore the reading frame of a loss-of-function SlGLK2 allele in tomato, ...
Fluorescent Tagging Toolkit Illuminates the Hidden Architecture of the Worm Cuticle
Researchers built 105 fluorescently tagged extracellular matrix proteins in C. elegans, creating a standardized atlas that reveals how the collagen-rich ...
Two-Layer Gene Editing Delivers Elite Herbicide-Tolerant Crops
Researchers combined structure-guided protein design with cis-regulatory editing at the native HPPD locus to create elite herbicide-tolerance alleles in rice ...
PrimeStack: New Gene-Stacking Tool Writes Large DNA Cargos Into Rice Genomes at Precise Sites
Scientists have developed PrimeStack, a break-free genome-editing platform that combines prime editing with the Bxb1 integrase to insert large multigene ...
Wild Relatives Hold the Genetic Keys to Future-Proof Crops, Review Finds
A new review argues that crop wild relatives hold vast untapped genetic diversity, but translating it into better cultivars requires ...
Eight Years After the Gene-Edited Babies Scandal, China’s Criminal Law Still Has Gaps to Close
A new legal analysis argues that China's 2021 criminal ban on implanting gene-edited or cloned embryos, adopted after the 2018 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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