Tag: gene regulatory networks

A neural ordinary differential equation model learned joint RNA and chromatin dynamics in mouse germinal-center B cells, predicted mutation effects ...

A genomic and transcriptomic study found that A. oryzae overlaps with two A. flavus populations, suggesting multiple domestication events, alongside ...

A mini-review finds that AI-assisted reconstruction of cell-state-specific gene regulatory networks can illuminate tumor plasticity and drug resistance, but experimental ...

A new theoretical paper argues that a single conserved regulatory architecture sustains biological coherence across evolution and, when disrupted within ...

Researchers introduced TAKO, a fast and interpretable method that ranks likely targets of a single-gene knockout using only wild-type single-cell ...

Researchers at the University of Wisconsin–Madison have built a cross-species atlas of gene regulatory networks governing early mammalian neurogenesis, revealing ...

A new computational pipeline called HiFIseek systematically links damaging non-coding mutations to cancer genes, revealing that regulatory regions of drivers ...

Researchers have developed CardamomOT, an optimal transport-based framework that jointly infers gene regulatory networks, reconstructs unobserved protein trajectories, and enables ...

A new mathematical framework ranks which stable cellular states and multistable switches are most prevalent across all monotone Boolean models ...

A paired single-nucleus RNA and chromatin atlas with spatial transcriptomics charts how the human meninges, their blood-brain barrier endothelium, yolk ...