Tag: gene regulatory networks

A multimodal atlas of the developing human heart reveals 21 tissue niches, shows fetal pacemaker cells recruiting their own nerve ...

A new deep learning framework called TERfinder integrates multi-omics data to map enhancer-promoter interactions in myeloid leukemia, pinpointing key regulatory ...

Researchers have developed RegPathTopic, a deterministic topic-modeling framework that builds traceable regulatory vocabularies from transcription factor-target graphs and benchmarks them ...

Single-cell mapping of human B cell activation reveals that memory cells are intrinsically biased toward becoming plasma cells while naive ...

Researchers in Japan used organoid-line-specific regulatory network analysis on patient-derived colorectal cancer organoids to uncover drug-response-associated subnetworks that conventional biomarkers ...

A new physics-in neural network framework called GRNvelo unifies gene regulatory network dynamics with cell population behavior, accurately reconstructing cell ...

A new review in Advanced Science maps how in vivo direct reprogramming converts resident cells into functional replacements for damaged ...

KAIST researchers developed NUDGE, a computational framework that redirects cell fate with a single temporary intervention by harnessing the natural ...

Researchers have developed CRISGI, a computational framework that detects critical transient gene interactions presaging abrupt disease shifts across bulk, single-cell, ...

A new computational simulator called TFdisc predicts how brain cells respond to transcription factor perturbations, revealing that schizophrenia and autism ...