RNA Molecules Found to Drive Aggressive Leukemia Through Oncocondensates
Vienna researchers developed the bicon-seq method and discovered that the long non-coding RNA Gas5 is a functional component of leukemia-driving ...
Tag: Gene regulation
Genetic Deletion Rewrites the Rules of Methylation Inheritance in Plants
The discovery that VIM2 and VIM4 act as dosage-sensitive negative regulators of CG methylation maintenance forces a reconsideration of how ...
Apple gene switch discovered that keeps tree branches in check
Researchers in China have identified the MADS-box transcription factor MdAGL29 as a negative regulator of shoot branching in apple, showing ...
Massive Cell-by-Cell Map Reveals the Cerebellum’s Hidden Role in Alzheimer’s Disease
A single-nucleus multiome atlas of over 100,000 brain cells reveals disease-linked regulatory programs and potentially causal genetic variants in the ...
AI Tool PeTMiner Uncovers Hidden RNA Regulators That Shape Plant Gene Expression
Researchers have developed PeTMiner, a deep learning framework that uses a plant RNA foundation model, hierarchical attention, and adaptive loss ...
Human knees pay an evolutionary price for walking upright, study finds
Israeli and Japanese researchers report in Nature that reduced cartilage cushioning molecules, an evolutionary trade-off tied to human traits, explain ...
Hidden DNA Repeats Point to a New Alzheimer’s Risk Gene, Long-Read Study Reveals
A hybrid long-read and short-read sequencing study has identified a common CCG repeat in the FAM193B promoter as a genome-wide ...
Ancient Jumping Genes Turn Out to Be Hidden Architects of the Human Cortex
A Nature Neuroscience commentary highlights new evidence that genetic variants within Alu transposable elements help shape the size and structure ...
Yeast Cell Model Shows Cell Geometry Reshapes Gene Network Predictions
A spatially resolved model of the yeast galactose switch shows that intracellular architecture, especially ER-bound translation, changes gene regulation predictions.
Why Some Neurons Survive: Identity Maintenance May Set the Threshold of Neurodegeneration
A new PLOS Biology essay proposes that a neuron's capacity to maintain its subtype-defining gene-regulatory machinery may set the stress ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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