How Embryos Police the Evolution of Duplicated Genes in Salmon
A massive multiomics study of Atlantic salmon and rainbow trout shows that developmental constraints, particularly at the vertebrate phylotypic period, ...
Tag: Gene regulation
Hidden RNA Switches in the Human Brain Reveal New Genetic Routes to Alzheimer’s and Parkinson’s Disease
A single-cell atlas of alternative polyadenylation across two million human brain cells reveals a hidden genetic regulatory layer that explains ...
Ancient Jumping Genes Help Explain How DNA Variants Shape the Human Cortex
A massively parallel reporter assay of 9,092 cortical-structure-associated variants reveals that Alu retrotransposons, Wnt signaling and transcription factor expression jointly ...
Hospital Superbug’s Iron Sensor Revealed as New Target Against Antibiotic Resistance
A UMBC-led team has revealed that Pseudomonas aeruginosa uses a two-protein switch, BqsS and BqsR, to sense iron inside and ...
NIH Backs Bold Epigenetics Quest to Decode How Immune Cells Walk the Tightrope Between Defense and Disease
Van Andel Institute's Dr. Derek Janssens has received a nearly $4.6 million NIH New Innovator Award to develop tools that ...
Scientists Discover the Genetic Brake That Stops Lilies From Surviving Heat Waves
A genome-wide survey of lily heat shock transcription factors has identified LdHSFC1 as a heat-induced repressor that directly suppresses the ...
Scientists Rank Genetic Switches That Power Gene Control in Sperm-Producing Cells
A comparative study of mouse germ cell promoters finds the Ldhc promoter drives the strongest and most reliable transgene expression ...
Epigenetics Beyond the Clinic: A New Journal Charts the Field’s Next Frontier
The launch of the open access journal Epigenetics Communications marks a push to understand dynamic epigenetic networks, publish negative results ...
Iron’s Master Switch: How Cells and the Body Keep the Perfect Balance
A new review maps the molecular circuits, from intracellular IRE-IRP sensors to the liver hormone hepcidin, that keep the body's ...
A Tiny Glycine Repeat May Have Helped Mammals Grow Hair, Study Suggests
Researchers report that a polyglycine repeat inserted into the Hoxc13 transcription factor during mammalian evolution dramatically expanded its genome-wide DNA ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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