Tag: Gene regulation

Using native long-read nanopore sequencing, researchers have simultaneously mapped 5mC and 5hmC across the whole genome of human neuronal nuclei, ...

UniLoopNet predicts enhancer–promoter, enhancer–enhancer, CTCF-mediated, and stripe-associated chromatin interactions from DNA sequence using a multi-task deep learning framework.

A study in BMC Medical Genomics finds that miR-183-5p is upregulated in the serum of adolescent idiopathic scoliosis patients, shows ...

A donor-heart study finds that schizophrenia is associated with a cardiomyocyte state in which molecular output is preserved but regulatory ...

University of Basel researchers used single-molecule chromatin tracing in C. elegans embryos to reveal three distinct types of large heterochromatin ...

A newly characterized CaHY5-CaNAC83 regulatory pathway in pepper activates anthocyanin biosynthesis genes, pointing to new tools for purple-pepper breeding.

A multi-dataset bioinformatics analysis prioritized 2,505 candidate Arabidopsis genes associated with links between m6A RNA modification and alternative polyadenylation under ...

A single-cell atlas of 232,251 developing fruit fly neurons links gene activity to regulatory DNA switches and suggests that neuronal ...

Penn State researchers found that cancer-linked BRD4 can bind nucleosomes through both DNA contacts and recognition of modified histones, challenging ...

A new theoretical framework proposes that early adversity alters the developing biological architecture through which later inputs are transformed into ...