Selenium Shields the Liver: Trace Element Preserves Bile Pump and Blocks Cholestatic Damage in Rats
New research shows that selenium pretreatment at 1 mg/kg protects rats from chemically induced cholestatic liver injury by preserving BSEP ...
Tag: FXR
Common Bile Acid Drug Unlocks a Hidden Human Brake on Radiation-Driven Cancer Immunity
Researchers have identified a human-specific FXR-TRIM22-STAT1 checkpoint that suppresses radiation-induced antitumor immunity, and shown that the clinically approved bile acid ...
SMRT Corepressor Emerges as Master Regulator of Bile Acid Homeostasis Through Nuclear Receptor Control
A new review in Experimental & Molecular Medicine describes how the corepressor SMRT tunes nuclear receptor signaling to regulate bile ...
Bile Acids Emerge as Master Regulators Linking Gut Microbes, Immunity and Cancer
A new commentary in Holistic Integrative Oncology argues that bile acids act as master signaling molecules linking liver metabolism, gut ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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