Review links macrophage mitochondrial imbalance to atherosclerosis progression
A 2026 review finds that experimental manipulation of macrophage mitochondrial quality control can change plaque development, but most supporting evidence ...
Tag: foam cells
Overactive Inflammasome in Artery Muscle Cells Drives Dangerous Vessel Thickening in Mice
A new mouse study shows that hyperactive NLRP3 inflammasome signaling within vascular smooth muscle cells drives inflammation, pyroptosis, lipid accumulation, ...
Parkinson’s Protein Alpha-Synuclein Drives Clogged Arteries by Jamming Cellular Recycling
New research shows that alpha-synuclein, best known for its role in Parkinson's disease, enters macrophages through the protein FLOT1, blocks ...
Repurposed cancer and blood pressure drugs show promise against artery-clogging foam cells
Researchers repurposed the approved drugs talazoparib, tivozanib and isradipine as candidate inhibitors of VAV2 signaling that reduced oxidized LDL uptake ...
New Molecular Driver of Atherosclerosis Identified: PLCE1 Pushes Artery Disease Forward
New research in Cell Death Discovery shows that the enzyme PLCE1 worsens atherosclerosis by damaging endothelial function and fueling macrophage ...
Blocking a Single Kinase May Steer Immune Cells Toward Safer Atherosclerotic Plaques
New research shows that removing protein kinase C delta reprograms macrophage metabolism to suppress inflammatory pyroptotic cell death and stabilize ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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