Stevia Extract Shields Diabetic Livers by Taming Iron-Driven Cell Death
A new rat study shows aqueous stevia extract protects diabetic livers by suppressing ferroptosis, boosting antioxidant enzymes, and reducing inflammation.
Tag: ferroptosis
Copper Overload Silences a Key Liver Fat Gene, Pushing Cells Into Ferroptosis in Wilson Disease
New research shows that copper accumulation in Wilson disease shuts down the PPARα–FABP1 fat-handling axis in hepatocytes, sensitizing them to ...
Bacterial Toxin Hijacks Mitochondria to Trigger Fatal Cell Death in Bovine Mastitis
New research reveals that the Staphylococcus aureus virulence factor Sph disrupts mitochondrial cristae through Mic60, releasing mtDNA that activates the ...
Astrocyte Redox Switch Linked to Synapse Damage in Multiple Sclerosis
A new single-cell and animal study links SLC7A11-high astrocyte states to antioxidant failure and synaptic remodeling in multiple sclerosis, pointing ...
Orphan Nuclear Receptor Ligands Trigger Ferroptosis and Reshape Immunity in Colon Cancer
New research shows that synthetic ligands for the orphan nuclear receptors NR4A1 and NR4A2 induce iron-dependent cell death in colon ...
Iron and Copper Cell Death Pathways May Hold Key to Beating Immunotherapy Resistance
A new review in Medical Oncology argues that simultaneously inducing the iron-driven cell death ferroptosis and the copper-driven cuproptosis, tuned ...
How a Common Grain Toxin Hijacks Cells—and How Probiotics Fight Back
A new review maps how the mycotoxin deoxynivalenol hijacks ribosomal and cellular signaling networks to drive intestinal, immune, neurological and ...
Gut Metabolite 2,8-Dihydroxyquinoline Shields Sperm Cells From Iron-Driven Cell Death
A gut microbiota-derived antioxidant metabolite, 2,8-dihydroxyquinoline, reverses oligoasthenozoospermia in mice by binding the kinase MAPK14 and blocking ferroptotic death of ...
Nerve Fibers Invade the Aging Lens, Revealing How Cataracts Take Hold
A single-cell atlas of 554 human cataract capsules reveals that nerve-like fibers invade the aging lens through an NRG1-ERBB3 signaling ...
Cellular Contact Points Called MAMs Emerge as Central Players in Heart Attack Damage
A new review in the Journal of Translational Medicine argues that mitochondria-associated endoplasmic reticulum membranes integrate lipid metabolism and ferroptosis ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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