A Methylation Signature in Brain Fluid Predicts Who Survives a Deadly Stroke
Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...
Tag: ferroptosis
Scientists Map the Iron Recycling Switch That Decides Whether Cells Live or Die
A new review in the Journal of Translational Medicine maps how NCOA4-mediated ferritinophagy controls iron release and ferroptosis, cataloguing small-molecule ...
Kale Nanovesicles Boost Cancer Drug’s Kill Switch in Liver Tumor Cells
Researchers at Yeditepe University report that kale-derived exosome-like nanovesicles combined with the dual PI3K/mTOR inhibitor dactolisib trigger apoptosis and alter ...
Electron-Pumping Photosensitizer and Nanozyme Team Up to Kill Breast Cancer Cells Three Ways at Once
Researchers engineered a cyanine photosensitizer with a benzophenone electron-pumping group and loaded it into a pH-responsive, hyaluronic acid-coated iron nanozyme ...
Plant-Derived Molecule KGA-1002 Strikes GRP94 to Collapse Liver Cancer’s Protein Folding Machinery
A synthetic guaianolide dimer derived from a plant sesquiterpenoid selectively covalently binds the ER chaperone GRP94 at serine 106, triggering ...
Electroacupuncture Meets a Smart Hydrogel to Rebuild Injured Spinal Cords
A conductive, antioxidant hydrogel loaded with stem cells and paired with electroacupuncture suppressed ferroptosis and restored motor function in mice ...
Red Blood Cell Hitchhiking Delivers Oxygen and Paclitaxel to Crush Drug-Resistant Breast Cancer Metastases
Scientists have engineered red blood cell-hitchhiking liposomes that co-deliver hemoglobin and paclitaxel to lung metastases, reversing hypoxia-driven drug resistance and ...
RNA-Binding Protein Switch Could Sensitize Deadly Pancreatic Cancer to Radiation
Researchers in Beijing have identified a PUM2-PAFAH1B1 regulatory axis that triggers ferroptosis and overcomes radioresistance to iodine-125 seed therapy in ...
How a Common Hormonal Disorder Disrupts the Placenta and Programs Disease in Offspring
A new review in Reproductive Sciences details how the metabolic disturbances of polyendocrine metabolic ovarian syndrome, the renamed polycystic ovary ...
Plant-Powered Hydrogel Halts Cell Death to Heal Diabetic Wounds
A bio-inspired hydrogel combining baicalein, glycyrrhizic acid nanofibers, gelatin and zinc ions suppresses ferroptosis in endothelial cells and closed 96 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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