Iron, Lipids and Cell Death: Ferroptosis Biomarkers Emerge as Clues to Vitiligo Activity
A new case-control study finds that serum markers of ferroptosis, including ACSL4, MDA and ROS, are elevated in vitiligo vulgaris ...
Tag: ferroptosis
Circular RNA circLPAR3 blocks ferroptosis to fuel chemotherapy resistance in prostate cancer
Researchers at Nanjing Medical University report that the m6A-stabilized circular RNA circLPAR3 suppresses ferroptosis through the PCBP2/CHAC1 axis, driving docetaxel ...
MOTS-c: The Tiny Mitochondrial Peptide That Behaves Differently in Health and Cancer
A new review argues that the mitochondrial peptide MOTS-c acts as a context-dependent stress signal with protective roles in metabolic ...
Scientists Uncover How Oral Cancer Cells Outsmart Cisplatin by Blocking Ferroptosis
New research reveals that the secreted protein DKK1 helps oral squamous cell carcinoma resist cisplatin by keeping the SLC3A2 cystine ...
Gated Nanoreactor Turns Tumor Glucose Into Carbon Monoxide to Boost Mild Heat Therapy
A ZIF-8-gated cascade nanoreactor converts tumor glucose into hydrogen peroxide and carbon monoxide, depleting ATP and suppressing HSP70 so that ...
Chemical Tag on RNA Helps Melanoma Dodge Ferroptosis, Study Finds
New research shows that the m6A reader protein YTHDF2 promotes melanoma progression by destabilizing HMOX1 mRNA and shielding tumor cells ...
PET tracer lights up ferroptosis to track liver cancer immunotherapy in real time
Researchers combined anti-PD-L1 immunotherapy with the PARP inhibitor Olaparib to trigger ferroptosis in liver cancer and used the SLC7A11-targeted PET ...
Diabetes Drug Metformin Surprisingly Blocks Ferroptotic Cell Death in Cancer Cells
New research shows that metformin and phenformin suppress cysteine deprivation-induced ferroptosis in cancer cells by dampening mitochondrial hyperpolarization, oxygen consumption, ...
Triaptosis: Scientists Unveil a New Form of Cell Death Centered on Endosomes
A new review in Cell Death & Discovery proposes triaptosis, an endosome-centered form of ROS-regulated cell death driven by oxidative ...
Kidney Disease in Newborn Mice Drives Iron Buildup in the Developing Brain
A new mouse study shows that severe kidney disease in newborns causes iron to accumulate throughout the developing brain, offering ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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