Mitochondrial Citrate Transporter SLC25A1 Drives Skin Cancer Through Histone Acetylation
Researchers in China have shown that the mitochondrial citrate transporter SLC25A1 promotes cutaneous squamous cell carcinoma by boosting histone H3 ...
Tag: epigenetics
Cryo-EM Reveals How Polycomb Repressive Complex 1 Assembles, Works and Finds Its Targets
Ciapponi and colleagues have determined the cryo-EM structure of the canonical PRC1 holocomplex, revealing how its architecture coordinates assembly, H2A ...
Proteasome Gatekeeper RPT2a Controls When Plants Flower by Destroying a Key Histone Protein
New research reveals that the proteasome subunit RPT2a regulates flowering time in Arabidopsis by promoting the degradation of the chromatin ...
Hidden Enzyme KMT9 Helps Prostate Tumors Evade Immune Attack
New research reveals that the epigenetic enzyme KMT9 orchestrates immune evasion in prostate cancer by recruiting suppressive myeloid cells and ...
Lactate Rewrites the Epigenome to Tear Down the Retina’s Protective Barrier in Diabetes
New research reveals that lactate-driven histone H3K9 lactylation activates a PTK2–FMNL2 signaling axis that breaks down the retinal endothelial barrier ...
Scientists Map How Tumours Push Immune Cells Into Exhaustion
A review in Experimental & Molecular Medicine examines how chronic antigen exposure and a hostile tumour microenvironment reprogram T cells ...
Cigarette Smoke Disrupts Mitochondria in Airway Cells but Leaves Mitochondrial DNA Methylation Largely Untouched
New research shows cigarette smoke extract impairs mitochondrial respiration and transiently boosts mitochondrial gene expression in airway cells without significantly ...
Reading the Genome One Molecule at a Time: A Practical Guide to Single-Molecule Genomics
Leading genome researchers have published a practical guide in Nature Reviews Molecular Cell Biology explaining how single-molecule genomics can reveal ...
Epigenetic Marks and Jumping Genes Decide Which Parental Genome Rules Mustard
New research shows that asymmetric DNA methylation, histone marks and transposable element insertions explain why one parental genome dominates gene ...
Ageing Bone Cells Lose a Key Epigenetic Brake, Driving Osteoporosis
New research reveals that loss of the epigenetic regulator Prmt6 triggers a Sting–Ifitm3 immune cascade that senesces osteoblasts and accelerates ...
-
Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
-
University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
-
Bee body mass, pathogens and local climate influence heat tolerance
-
Researchers record first-ever images and data of a shark experiencing a boat strike
-
Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
Embark on a thrilling journey of discovery with Scienmag.com—your ultimate source for cutting-edge breakthroughs. Immerse yourself in a world where curiosity knows no limits and tomorrow’s possibilities become today’s reality!