Hidden Protein Brake on Plaques Reveals New Path Beyond Cholesterol
Researchers in Shanghai have discovered that the protein TXNIP suppresses dangerous plaque angiogenesis by degrading the glycolytic enzyme HK2 and ...
Tag: epigenetics
Cash Transfers Tested as a Tool to Slow Biological Ageing in Children and Mothers
A randomised controlled trial has investigated whether unconditional cash transfers can alter epigenetic measures of ageing and cognitive development in ...
Mitochondrial DNA Methylation Unchanged in Down Syndrome, Study Finds
The first study to examine mitochondrial D-loop methylation in Down syndrome finds no significant differences in methylation or mitochondrial DNA ...
Stress Sensor Reveals How Malaria Parasites Switch to Transmission Mode
Researchers have identified the transcription factor AP2-HS and a GDV1–antisense RNA feedback loop as the mechanism by which malaria parasites ...
AI Tumor Classifier Proves Its Worth in 516 Tough Brain Cancer Cases
A large evaluation of the Bethesda v3 DNA methylation classifier shows robust performance in routine brain tumor diagnostics, correctly classifying ...
Why aging immune systems turn against the body: a two-step model of B cell autoreactivity
A new GeroScience review proposes that B cell-intrinsic aging relaxes immune tolerance while chronic inflammaging selectively expands autoreactive B cell ...
Bacterial Inoculation Rewrites the Coral Epigenome, Study Reveals
A new Nature Communications study shows that inoculating corals with beneficial bacteria produces measurable changes in the coral host's epigenome, ...
CRISPR Methylation Sensing Moves Toward Next-Generation Epigenetic Diagnostics
A new review details how CRISPR-Cas enzymes can be engineered to detect DNA and RNA methylation with single-nucleotide precision, charting ...
Decades-Old Newborn Blood Spots Yield High-Quality DNA Methylation Data With Tiny DNA Inputs
A pilot study shows the Illumina MethylationEPIC v2.0 array produces high-quality DNA methylation data from decades-old Swedish newborn blood spots ...
CRISPR Screens Reveal DNMT3A’s Dual Role in Tumor Immune Evasion
In vivo CRISPR screens reveal that the epigenetic enzyme DNMT3A can both preserve and suppress tumor immune visibility, reshaping how ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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