Tiny Gene Regulators Show Promise Against the Deadliest Childhood Brain Tumors
New research shows that restoring the microRNAs miR-34a and miR-34c suppresses the survival, migration, invasion, and stemness of pediatric grade ...
Tag: epigenetics
High Blood Sugar Rewrites Pancreatic Cell Chemistry, Driving Stress Granule Buildup in Diabetes
New research shows that diabetes elevates the histone mark H3K4me1 in pancreatic acinar cells, driving stress granule formation under high ...
Massive Epigenetic Study Reveals Why Parkinson’s Disease Strikes Men and Women Differently
A two-stage epigenome-wide meta-analysis of more than 2,000 individuals has identified thousands of DNA methylation sites where Parkinson's disease affects ...
Jumping genes may explain why big dogs age faster and die younger
A large-scale study of 864 dogs finds that giant breeds lose methylation control over LINE1 jumping genes far faster than ...
Chemical Tag on mRNA Reveals Hidden Switch That Controls Hair Growth Cycles
A new PLOS Genetics study shows that the RNA modification enzyme METTL1 controls hair follicle cycling by stabilizing HOXC13 messenger ...
Injectable Piezoelectric Hydrogel That Strengthens Itself Rewires Stem Cell Genes to Rebuild Bone
A self-reinforcing injectable hydrogel converts body movement into electrical signals that trigger calcium-dependent histone acetylation and accelerate bone regeneration in ...
Computational Microscope Opens a New Window on Chromatin Folding
An international team has developed OpenCGChromatin, an open-source simulation tool that acts as a computational microscope to reveal how chromatin ...
Aging May Stem From a Genome-Wide Shift That Sidelined Cellular Maintenance
A new GeroScience study finds that after sexual maturity, housekeeping genes lose transcriptional share to specialized integrative genes across species, ...
How Genes, Hormones and Weather Decide When a Flower Blooms
A sweeping review explains how MADS-box genes, microRNAs, hormones and environmental signals jointly control flowering, floral organ identity and sex ...
Hidden Genome Folds Silence Two Tumor-Suppressing Genes in Aggressive Breast Cancer
Researchers have discovered that DNA methylation evicts the architectural protein CTCF from the HOXD locus, collapsing a chromatin loop that ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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