Lost Epigenetic Guardian CBX7 Emerges as Key Driver and Drug Target in Glioblastoma
A new review shows that the epigenetic regulator CBX7 acts as a tumor suppressor in glioblastoma, and that restoring its ...
Tag: epigenetics
Mitochondrial Enzyme SUCLG2 Emerges as a Tumor Suppressor in Colorectal Cancer
Researchers found that the mitochondrial enzyme SUCLG2 suppresses colorectal cancer by lowering SAM levels to demethylate GADD45G and reactivate p53-mediated ...
Epigenetic Enzyme Keeps Spinal Disc Cells Metabolically Balanced, Study Finds
New research shows that the epigenetic enzyme HDAC1 preserves metabolic balance in nucleus pulposus cells through post-translational modification interactions with ...
Epigenetic Age Tests Face Expert Backlash Over Reliability, Privacy and Ageism
A real-time Delphi study of French and Canadian experts finds widespread concern over the reliability, utility and legitimacy of direct-to-consumer ...
Common Gut Molecule Reverses Brain Damage From Prenatal Opioid Exposure
New research in Translational Psychiatry shows that sodium butyrate, a gut-derived histone deacetylase inhibitor, can rescue long-term neurodevelopmental deficits caused ...
Epigenetic Switches Could Arm Rice Against Its Deadliest Pathogens
A comprehensive review reveals how DNA methylation, histone modifications and non-coding RNAs regulate rice immunity and could enable epigenetic breeding ...
Lung Immune Cells Show Lasting Epigenetic Changes in Long COVID Patients
A Swedish longitudinal study finds that lung immune cells, but not blood cells, undergo lasting DNA methylation changes in long ...
Epigenetic Switch That Shields Cartilage From Osteoarthritis Is Revealed
A new study reveals that the epigenetic enzyme DOT1L protects cartilage in osteoarthritis by boosting ITCH expression, which in turn ...
Cancer Reshapes the SUMOylation Landscape to Sabotage Muscle Function, Study Finds
New research reveals that cancer reorganizes the SUMOylation landscape in skeletal muscle and alters L3mbtl2-mediated transcriptional control, offering a molecular ...
Cohesin Builds Molecular Fences That Keep Active Genome Domains From Mixing
New research shows that the cohesin complex acts as a molecular barrier in living human cells, preventing condensed euchromatic domains ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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