Master Switch PRDM1 Steers Natural Killer Cell Maturation and Cancer Defense
A new review details how the transcriptional repressor PRDM1 orchestrates natural killer cell maturation, effector function, and tumor suppression, with ...
Tag: epigenetics
How Maize Remembers Drought: Epigenetic Memory and Seed Priming Could Shield the World’s Vital Cereal Crop
A new review reveals how maize stores molecular memories of past droughts through histone marks, DNA methylation and transposable elements, ...
Genetic Deletion Rewrites the Rules of Methylation Inheritance in Plants
The discovery that VIM2 and VIM4 act as dosage-sensitive negative regulators of CG methylation maintenance forces a reconsideration of how ...
Esophageal Cancer at a Crossroads: Landmark Review Maps Molecular Drivers and Next-Generation Therapies
A comprehensive Chinese Medical Journal review led by Professor Feng Wang synthesizes five years of advances in esophageal cancer, highlighting ...
Beyond BRD4: Bromodomain Protein BRD9 Emerges as a New Regulator of Retroviral Latency
A new review highlights how the bromodomain protein BRD9, a core component of the ncBAF chromatin-remodeling complex, has emerged as ...
DNA Methylation Study Fails to Replicate Epigenetic Scars of Childhood Maltreatment
A preregistered replication study in Translational Psychiatry found that reported DNA methylation signatures of childhood maltreatment subtypes largely failed to ...
Social Media Overuse Linked to Stress-Gene Methylation in First Longitudinal Epigenetic Study
A longitudinal study of depressed patients and healthy controls finds preliminary links between problematic social media use and DNA methylation ...
Epigenetic Switch Controls How Flowers Decide When to Stop Growing
Researchers at Zhejiang University have discovered that the epigenetic regulator HDC1 controls sepal length in Arabidopsis by repressing protein phosphatase ...
Disc Degeneration Traced to a Histone Switch That Silences the Cell’s Mitochondrial Cleanup Crew
A new study shows that the chromatin protein CBX3 accelerates disc degeneration by silencing the SESN2 gene through H3K9me3 marks, ...
Chemokine Gene Methylation Tied to Liver Inflammation in Chronic Hepatitis B
Researchers found that reduced methylation of the CXCL16 gene promoter in chronic hepatitis B patients tracks with elevated chemokine expression ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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