Human osteoclast formation drives widespread DNA methylation remodelling, study finds
A genome-wide study of human cells finds 9,006 differentially methylated CpG sites and 1,526 differentially methylated regions during osteoclast differentiation.
Tag: epigenetics
Metabolic Rewiring Emerges as a Central Driver of Liver Cancer Growth and Treatment Resistance
A new review argues that glucose, lipid, and amino acid metabolism form one interconnected network driving hepatocellular carcinoma growth, immune ...
Gingival fibroblast-derived iPSCs show broad methylation convergence with residual somatic patterns
A methylation comparison of human gingival fibroblasts, their derived iPSCs and an embryonic stem-cell reference found broad pluripotent-state convergence alongside ...
Metabolic Enzyme BCAT1 Drives Endometriosis Cell Growth Through Histone Acetylation
A cell study finds that the enzyme BCAT1, elevated in endometriosis tissue, promotes proliferation and migration of ectopic endometrial stromal ...
T cells in AML are not uniformly dysfunctional, researchers argue in new analysis
A BMC Medicine debate article argues that T cells in acute myeloid leukemia are not uniformly dysfunctional and that assessing ...
Molecular Markers May Predict Pituitary Tumor Invasion
A new review in Frontiers in Endocrinology synthesizes molecular biomarkers, including DNA methylation and liquid biopsy indicators, that may help ...
Research report: Medicinal plants in a changing climate: evolutionary genomics for resilience and conservation
A new review argues that conserving medicinal plants under climate change requires protecting adaptive genomic variation, not just species or ...
Urinary DNA methylation marker TAGMe offers preoperative risk stratification in urothelial carcinoma
A urine-based DNA methylation marker, TAGMe, was associated with poorer outcomes in urothelial carcinoma and improved preoperative risk prediction in ...
THOR hypermethylation drives hTERT reactivation in cervical cancer
A study of Indian cervical cancer patients links THOR hypermethylation to hTERT reactivation and reduced menin recruitment, independent of HPV ...
Gladstone Scientists Melanie Ott and Alex Marson Join National Academy of Medicine
Gladstone Institutes physician-scientists Melanie Ott and Alex Marson have been elected to the National Academy of Medicine in recognition of ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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