Study identifies histidine ‘pendulum’ mechanism underlying high activity of Group A [FeFe]-hydrogenases
An experimental and simulation study found that two surface histidines form a proposed pendulum-like proton relay in Group A -hydrogenases, ...
Tag: enzyme structure-function relationship.
Enzyme’s Changing Shape Steers Molecular Recognition, Simulations Show
Molecular dynamics simulations of pyrimidine-nucleoside phosphorylase from Bacillus subtilis show that the enzyme's conformational state controls ligand retention and compound-specific ...
Scientists Pin Down the Three Amino Acids That Power a Coral Tree Seed Enzyme
Chemical modification, fluorescence, and structural studies have identified one carboxylate, one tryptophan, and one serine residue as the essential catalytic ...
Primate-Specific Control of UGCG, the Human Glycosphingolipid Gatekeeper
Glycosphingolipids may be tiny components of cell membranes, but they help govern some of biology’s most consequential decisions: how cells ...
Uncovering Nature’s Hidden Cytochrome P450 Enzymes
In a groundbreaking revelation that is set to redefine our understanding of enzyme biochemistry, researchers have uncovered a surprising divergence ...
Breakthrough Discovery: Water Molecules Play Active Role in Driving Gene Transcription
In a groundbreaking revelation that challenges long-standing assumptions in molecular biology, scientists have revealed that water molecules are not mere ...
Exploring Thermotoga Maritima Pullulanase Through Mutagenesis
Researchers are continually exploring the vast potentials of enzymes as biocatalysts in various industrial processes. Among these enzymes, pullulanases are ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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