Tag: drug resistance

A six-patient Italian real-world case series reports that asciminib achieved sustained molecular responses and a favourable cardiovascular safety profile in ...

Researchers have built ProteinTalks, an AI virtual cell model trained on more than 38 million time-resolved protein measurements from perturbed ...

A two-decade bibliometric analysis of nearly 5,000 studies maps how small molecule drug research transformed lung cancer therapy, revealing China's ...

An updated TB-Profiler extends genotypic drug-resistance prediction to 17 anti-tuberculosis drugs and adds transmission-tracking tools powered by a global database ...

New laboratory research shows progesterone increases vasohibin-2 expression and tubulin detyrosination in progesterone receptor-negative ovarian cancer cells, sharply boosting their ...

Genomic surveillance in Qujing, China, shows that NNRTI-resistant HIV-1 strains, largely of the CRF08_BC subtype, are circulating within local transmission ...

Boston Children's Hospital researchers discovered that the metabolic enzyme FAH moves into the nucleus of breast cancer cells and drives ...

A new mouse study shows that lung adenocarcinomas can evade KRAS inhibitors by reprogramming their cellular identity through transcription factors ...

Researchers in Japan used organoid-line-specific regulatory network analysis on patient-derived colorectal cancer organoids to uncover drug-response-associated subnetworks that conventional biomarkers ...

A new review in the Journal of Ovarian Research details how chronic inflammatory signaling pathways drive ovarian cancer progression and ...