Tag: drug resistance

A new study of paired glioblastoma specimens identifies Annexin A2 as an independent predictor of poor survival and a biomarker ...

New research shows that blocking the HSP90 chaperone forces stressed tumor cells to display GRP78 on their surface, making drug-resistant ...

Scientists have engineered red blood cell-hitchhiking liposomes that co-deliver hemoglobin and paclitaxel to lung metastases, reversing hypoxia-driven drug resistance and ...

A comprehensive review finds that the PI3K/AKT/mTOR signaling axis drives progression and therapy resistance in gastrointestinal cancers, but clinical success ...

A new computational study shows that the plant flavonoid kaempferol and the chemotherapy drug docetaxel both bind strongly to the ...

A new review in Medical Oncology synthesises evidence that tumours form functional synapses with neurons and exploit autonomic signalling to ...

Researchers report that the repurposed alcoholism drug disulfiram exploits a collateral vulnerability in chemotherapy-resistant ER+ breast cancer cells, and that ...

A sweeping review reveals how the RNA modification N6-methyladenosine orchestrates lung cancer progression, drug resistance, immunotherapy response, and survival prediction.

A new study shows that pachymic acid, a compound from the medicinal mushroom Poria cocos, synergizes with lenvatinib against hepatocellular ...

A multi-institutional retrospective study of 71 dogs found that the lomustine-based LOPP chemotherapy protocol achieved significantly higher complete remission rates ...