Organ-on-Chip Meets Digital Twin: Systematic Review Maps the Future of Drug Development
A new systematic review of 123 studies shows that pairing organ-on-chip devices with digital twin computational models is rapidly maturing ...
Tag: drug-induced liver injury
Liver Injury After CAR T-Cell Therapy May Be Driven by Cytokine Storm, Landmark Analysis Finds
A pharmacovigilance analysis of nearly five million adverse-event reports finds that liver injury after CAR T-cell therapy is predominantly early ...
Dandelion-Derived Compound Gets a Nanotech Upgrade to Shield the Liver From Drug Damage
Researchers built a nanocrystal-loaded mucoadhesive micropatch capsule that boosts the oral bioavailability of the dandelion compound taraxasterol 3.1-fold and protects ...
Gut Microbes Take the Wheel: How Bacterial Metabolites Remotely Steer the Liver’s Master Antioxidant Switch
A sweeping review in the Journal of Advanced Research details how gut bacterial metabolites such as butyrate, indoles, and urolithins ...
Gut Microbes and Metabolites Reveal Distinct Signatures Across Chronic Liver Diseases
A multi-omics study of 80 patients reveals etiology-specific gut microbial and metabolic signatures in chronic liver disease.
Schisandrin Lignans Stabilize GPX4 to Suppress Ferroptosis in Drug-Induced Liver Injury
Drug-induced liver injury, one of the most unpredictable complications of modern pharmacotherapy, may be driven by a molecular failure that ...
Unraveling Naringin’s Toxic Effects on Liver Injury
In recent years, there has been growing interest in the relationship between dietary compounds and liver health. A recent study ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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