Tag: drug discovery

BMC Pharmacology and Toxicology is recruiting new Editorial Board Members across five disciplines to sustain peer-review quality amid rising submissions.

New commentaries in Science Translational Medicine warn of rifampicin-resistant tuberculosis while highlighting prevention strategies and AI-driven antibiotic discovery as the ...

A new review argues that benzothiazole derivatives, acting through DHFR inhibition and heme detoxification, could yield next-generation antimalarials effective against ...

A computational study combining density functional theory and multi-target molecular docking finds that the Panax notoginseng compound notoginsenoside L1 binds ...

Chemists in Shenzhen have developed a nickel-catalysed reaction that converts simple enamines and alkynes into enantioenriched chiral allylic amines in ...

Researchers have developed the first selective inhibitors of the NVL ATPase, blocking 60S ribosomal subunit assembly to activate p53 and ...

A new integrated laboratory and computational study confirms that the flavonoid-rich leaves of Bauhinia variegata, long used by tribal healers ...

Researchers combined virtual screening, mutational analysis, molecular dynamics simulations, and antimicrobial testing to identify two promising small-molecule inhibitors of the ...

Machine learning and laboratory experiments have identified TGFBR1 as a novel molecular target of the mango compound mangiferin and shown ...

A computational screen of 1,000 plant compounds identifies the steroidal saponin hecogenin as a leading multitarget inhibitor candidate against Epstein–Barr ...