Azo Compound Shows Promise Against Chagas and Leishmania Parasites
A synthetic azobenzenoid compound called CaCS2 shows broad-spectrum activity against Leishmania amazonensis and Trypanosoma cruzi with low human cell toxicity, ...
Tag: drug discovery
Black Pepper Compound Piperine Emerges as Powerful Potential Parkinson’s Drug in Landmark Study
A new computational study shows that piperine, the pungent alkaloid of black pepper, binds the Parkinson's-related MAO-B enzyme more strongly ...
Dual PROTACs Close In on Two Disease Proteins at Once
A new review in Molecular Diversity charts the rapid rise of dual PROTACs, single molecules engineered to destroy two disease-driving ...
Twenty-Five Years of Cancer Research: Stunning Breakthroughs and Sobering Setbacks
Marking the 25th anniversary of Nature Reviews Cancer, six leading researchers assess the transformative advances and unfulfilled expectations of a ...
Dual-State Structures Reveal How Drugs Switch the Immune Receptor GPR84
Paired structural snapshots of GPR84 in different conformational states, combined with immune cell assays, reveal how ligands activate, block or ...
Chemists forge chiral piperidine mimics in a single asymmetric leap
Chemists at Chongqing University report the first catalytic asymmetric synthesis of chiral 2-azaspiroheptanes, delivering a powerful new piperidine bioisostere for ...
Phosphatases Emerge as Promising Targets Against Diabetic Kidney Disease
A comprehensive review argues that classical protein tyrosine phosphatases, long considered undruggable, are central drivers of diabetic kidney disease and ...
Bath Drug Discovery Spinout Wins National Emerging Technologies Competition
Revolver Therapeutics, a University of Bath spin-out building a new class of drug discovery tools, has won the Health category ...
Crown Bioscience Joins C-Path Coalition for New Approach Methodologies
TUCSON, Ariz., July 16, 2026 — Critical Path Institute’s® (C-Path) New Approach Methodologies Developer Coalition (NAMs-DC) has added Crown Bioscience ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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