Epigenetic Editing Steps Closer to the Clinic as Bioengineering Tools Mature
The EpiBio-24 conference in Amsterdam showcased maturing epigenetic engineering tools, durable gene silencing in animal models, and growing clinical momentum ...
Tag: DNA Methylation
Near-Perfect Long Reads Reveal Hidden Mosaicism Left Behind by CRISPR Gene Editing
Ultra-accurate targeted long-read sequencing of genome-edited zebrafish reveals widespread CRISPR-Cas9 mosaicism, with structural variants and off-target mutations inherited into the ...
Metal stress rewrites plant DNA methylation within minutes, review finds
A new review in Ecotoxicology shows that plants respond to heavy metal toxicity with rapid, targeted DNA methylation changes that ...
Systematic Review Uncovers How ATM Gene Defects Shape Blood Cancers
A new systematic review finds that mutations, methylation, and expression loss of the ATM DNA repair gene are recurrent and ...
Single Genetic Change May Strike Twice in Rare Anemia Case, Long-Read Study Suggests
Long-read multi-omics sequencing of a severe GPI deficiency case has uncovered a candidate dual-effect variant that may simultaneously destabilize an ...
qBiCo: New Quality-Control Test Exposes Hidden Flaws in DNA Methylation’s Gold-Standard Method
A new five-plex qPCR assay called qBiCo provides the first comprehensive quality control for bisulfite-converted DNA, revealing that commercial conversion ...
Light-Patterned DNA Tags Give Single-Cell Sequencing a Sense of Place
A new light-based barcoding technique called scSTAMP-seq stamps spatial coordinates onto individual cells using photocleavable DNA tags, enabling joint transcriptomic ...
Scientists Confront the Social Stakes of Epigenetic Editing and Environmental Health
Round table discussions at the 2024 Clinical Epigenetics International Conference exposed deep divisions among scientists over whether epigenetic editing is ...
Stable Jobs Don’t Shield Black Workers From Faster Biological Aging, DNA Study Finds
New research linking 33-year employment histories to epigenetic clocks finds that racial gaps in biological aging persist even among workers ...
How Plant Polyphenols May Rewrite the Epigenetic Damage That Drives Cancer
A new review details how reactive oxygen species drive cancer through reversible epigenetic damage and how dietary polyphenols such as ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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