A comprehensive review details technological breakthroughs in epigenome editing platforms and highlights emerging in vivo strategies for disease modeling and ...
A cross-sectional observational cohort study demonstrates that epigenetic age acceleration is associated with metabolic syndrome and vascular stiffness in adults ...
A cross-tissue machine learning framework utilizing Gene Ontology pathway-level DNA methylation scores accurately identified asthma status across multiple airway epithelial ...
A human stem cell model using LATS kinase inhibition reconstructs the emergence and three-dimensional self-organization of the human chorion without ...
A scientific review details how disrupted metabolic pathways regulate epigenetic remodeling in pulmonary vascular cells during pulmonary arterial hypertension.
A multi-omics Mendelian randomization analysis identified 13 candidate mitochondrial-related genes linked to congenital heart disease susceptibility, with POLG and EARS2 ...
Researchers analyzing 843 placental samples have identified sex-linked DNA methylation differences associated with early-onset preeclampsia across both male and female ...
A multi-omics study using East Asian-specific models has prioritized novel susceptibility genes and epigenetic markers linked to lung cancer risk.
A new Frontiers collection of seven studies shows that addiction's molecular changes are cell-type-specific, spanning epigenetics, RNA modification, and human ...
Researchers identified 22 cell-type-specific genetic associations linking immune cell gene expression to epigenetic aging clocks through Mendelian randomization and colocalization ...
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