Blood CXCL1 tracks Salmonella colonization in tumors, study finds
Sustained blood CXCL1 elevation tracked attenuated Salmonella colonization in four preclinical tumor models.
Tag: CXCL1
Chemokine CXCL1/8-CXCR1/2 axis drives inflammatory niche in NF1 tumors
A new study identifies the CXCL1/8-CXCR1/2 chemokine axis as a driver of the inflammatory tumor microenvironment and matrix remodeling in ...
Immune cells in the liver shield against alcohol-related damage, mouse study finds
A study in Cell Death Discovery reports that MAIT cells limit alcohol-associated liver injury in mice by using IL-10 to ...
Chemokine Signal Behind VEGF-Driven Retinal Neovascularization Identified
A new study shows that VEGF-driven retinal neovascularization depends on a VEGFR2-VEGFR3-ATF6-GRP78 signaling axis that induces the chemokines CXCL1/2 and ...
Psychological Stress Triggers Arthritis Flares Through an IL-6-Dependent Pathway
Researchers at Chiba University have traced how psychological stress reactivates rheumatoid arthritis: stress activates brown adipose tissue to release IL-6, ...
Hidden Immune Signal RSAD2 May Drive Endometrial Cancer Growth, Study Finds
A multi-omics study links the antiviral protein RSAD2 to CXCL1–CXCR1/2 signaling that recruits macrophages and drives endometrial cancer progression.
How Chronic Stress Feeds Liver Cancer: A Brain-Liver Loop Revealed in Mice
Researchers at Sun Yat-sen University have mapped a hypothalamic vagal circuit through which chronic stress raises acetylcholine in liver tumors, ...
Immune Cells Feed Breast Cancer Tumors as AI and DNA Testing Reshape Cancer Care
New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation, ...
Immune Cells Hand Esophageal Cancer Its Stem-Like Edge Through an HNF1A/CXCL1 Circuit
New research shows that myeloid-derived suppressor cells drive stem-like properties in esophageal squamous cell carcinoma through an IL-1 beta-regulated HNF1A/CXCL1 ...
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Mothers who receive childcare support from maternal grandparents show more parental warmth, finds NTU Singapore study
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University of Seville Breaks 120-Year-Old Mystery, Revises a Key Einstein Concept
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Bee body mass, pathogens and local climate influence heat tolerance
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Researchers record first-ever images and data of a shark experiencing a boat strike
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Groundbreaking Clinical Trial Reveals Lubiprostone Enhances Kidney Function
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